"beta-Arrestin 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-arrestin that functions similarly to BETA-ARRESTIN 1 in regulating signaling by G-PROTEIN-COUPLED RECEPTORS. It is expressed at high levels in the central nervous system where it may regulate signaling by SYNAPTIC RECEPTORS.
| Descriptor ID |
D000071560
|
| MeSH Number(s) |
D12.644.360.024.098.525.750 D12.776.157.057.005.525.750 D12.776.476.024.104.525.750 D12.776.543.090.525.750
|
| Concept/Terms |
beta-Arrestin 2- beta-Arrestin 2
- beta Arrestin 2
- ARRB2 Protein
- Arrestin, beta 2
- beta 2 Arrestin
- Arrestin-3
- Arrestin 3
|
Below are MeSH descriptors whose meaning is more general than "beta-Arrestin 2".
Below are MeSH descriptors whose meaning is more specific than "beta-Arrestin 2".
This graph shows the total number of publications written about "beta-Arrestin 2" by people in this website by year, and whether "beta-Arrestin 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Arrestin 2" by people in Profiles.
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Linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse neural tube development. Development. 2024 10 01; 151(19).
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Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling. Sci Signal. 2018 08 28; 11(545).
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Gene dosage-dependent negative regulatory role of ?-arrestin-2 in polymicrobial infection-induced inflammation. Infect Immun. 2013 Aug; 81(8):3035-44.
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Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):17085-90.
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Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2449-54.
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beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1601-6.
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Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature. 2000 Dec 07; 408(6813):720-3.
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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science. 2000 Nov 24; 290(5496):1574-7.
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Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science. 1999 Dec 24; 286(5449):2495-8.
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Synergistic regulation of beta2-adrenergic receptor sequestration: intracellular complement of beta-adrenergic receptor kinase and beta-arrestin determine kinetics of internalization. Mol Pharmacol. 1997 May; 51(5):800-8.