"beta-Arrestin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-arrestin that functions in the down-regulation of signaling by G-PROTEIN-COUPLED RECEPTORS. It is also a major regulator of INSULIN signaling via the ERK 1-2 PATHWAY, and many other signaling processes, especially in NEURONS and LEUKOCYTES.
| Descriptor ID |
D000071559
|
| MeSH Number(s) |
D12.644.360.024.098.525.500 D12.776.157.057.005.525.500 D12.776.476.024.104.525.500 D12.776.543.090.525.500
|
| Concept/Terms |
beta-Arrestin 1- beta-Arrestin 1
- beta Arrestin 1
- Arrestin-2
- Arrestin 2
- Arrestin, beta 1
- beta 1 Arrestin
- ARRB1 Protein
|
Below are MeSH descriptors whose meaning is more general than "beta-Arrestin 1".
Below are MeSH descriptors whose meaning is more specific than "beta-Arrestin 1".
This graph shows the total number of publications written about "beta-Arrestin 1" by people in this website by year, and whether "beta-Arrestin 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Arrestin 1" by people in Profiles.
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Competing Engagement of ?-arrestin Isoforms Balances IGF1R/p53 Signaling and Controls Melanoma Cell Chemotherapeutic Responsiveness. Mol Cancer Res. 2023 12 01; 21(12):1288-1302.
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Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res. 2009 Jul; 7(7):1064-77.
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Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):17085-90.
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Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. J Biol Chem. 2006 Mar 17; 281(11):7684-92.
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Hypoxia/ischemia modulates G protein-coupled receptor kinase 2 and beta-arrestin-1 levels in the neonatal rat brain. Stroke. 2004 Apr; 35(4):981-6.
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beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1601-6.
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Enhanced morphine analgesia in mice lacking beta-arrestin 2. Science. 1999 Dec 24; 286(5449):2495-8.
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999 Jan 29; 283(5402):655-61.