"Trefoil Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 60 amino acid (6.5 kDa) trefoil factor that contains a single trefoil domain. It is expressed primarily by surface EPITHELIAL CELLS of the GASTRIC MUCOSA, where it associates with MUCIN 5AC.
| Descriptor ID |
D000071163
|
| MeSH Number(s) |
D12.644.937.500
|
| Concept/Terms |
Trefoil Factor-1- Trefoil Factor-1
- Trefoil Factor 1
- Protein pS2
- pS2, Protein
- Trefoil Peptide 1
- TFF1 Peptide
- TFF1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Trefoil Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Trefoil Factor-1".
This graph shows the total number of publications written about "Trefoil Factor-1" by people in this website by year, and whether "Trefoil Factor-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trefoil Factor-1" by people in Profiles.
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Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis. Pancreas. 2011 Aug; 40(6):815-22.
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A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions. Breast Cancer Res Treat. 2010 Jul; 122(2):381-93.
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Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in human gastric carcinoma cells. Scand J Gastroenterol. 2008 Jan; 43(1):25-33.
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A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60.
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Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res. 2001 Oct 15; 61(20):7456-63.
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DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis. Cancer Lett. 2000 Feb 28; 149(1-2):125-34.
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PS2 mRNA expression adds prognostic information to node status for 6-year survival in breast cancer. Br J Cancer. 1998; 77(3):492-6.
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pS2 is an independent factor of good prognosis in primary breast cancer. Br J Cancer. 1993 Jul; 68(1):93-6.