Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling.

Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling. Clin Sci (Lond). 2019 01 31; 133(2):225-238.

View in: PubMed

subject areas

ADAM17 Protein
Animals
Cardiomegaly
Case-Control Studies
Cell Differentiation
Child
Child, Preschool
COS Cells
Female
Genetic Predisposition to Disease
HEK293 Cells
Heparin-binding EGF-like Growth Factor
Human Embryonic Stem Cells
Humans
Infant
Loss of Function Mutation
Male
Mutation, Missense
Myocytes, Cardiac
Phenotype
Signal Transduction
Tetralogy of Fallot

authors with profiles

RICHARD FINNELL