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BILL R. BRINKLEY

TitleDean Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address
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    Other Positions
    TitleDean Emeritus
    InstitutionBaylor College of Medicine
    DepartmentGraduate School of Biomedical Sciences
    DivisionGraduate Sch of Biomedical Sciences


    Collapse Research 
    Collapse research activities and funding
    S10RR012888     (BRINKLEY, BILL R)Apr 1, 1998 - Mar 31, 1999
    NIH/NCRR
    DELTAVISION OPTICAL MICROSCOPY WORKSTATION
    Role: Principal Investigator
    S10RR002728     (BRINKLEY, BILL R)Apr 1, 1986 - Mar 31, 1987
    NIH/NCRR
    JEOL 1200 EX ELECTRON MICROSCOPE
    Role: Principal Investigator
    R37CA041424     (BRINKLEY, BILL R)Jun 1, 1985 - May 31, 1996
    NIH/NCI
    MITOSIS IN NORMAL AND NEOPLASTIC CELLS
    Role: Principal Investigator
    R01CA041424     (BRINKLEY, BILL R)Jun 1, 1985 - May 31, 1988
    NIH/NCI
    MITOSIS IN NORMAL AND NEOPLASTIC CELLS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brinkley WB. Romancing mitosis and the mitotic apparatus. Mol Biol Cell. 2014 Nov 01; 25(21):3270-2. PMID: 25360048; PMCID: PMC4214772.
      Citations: 1     Fields:    Translation:AnimalsCells
    2. Brinkley BR. Mitotic checkpoints, MUGs and kinetochores. Cell Cycle. 2013 Jun 15; 12(12):1822-3. PMID: 23759568; PMCID: PMC3735692.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 2013 Apr; 21(2):101-6. PMID: 23580138; PMCID: PMC3627038.
      Citations:    
    4. Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR, Mancini MA. A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol. 2012 Apr; 10(2):161-78. PMID: 22084958; PMCID: PMC3323936.
      Citations: 5     Fields:    Translation:HumansCells
    5. Slattery SD, Mancini MA, Brinkley BR, Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94. PMID: 19713763.
      Citations: 37     Fields:    Translation:HumansCells
    6. Brinkley BR. Cell motility and the cytoskeleton in transition. Cell Motil Cytoskeleton. 2009 Aug; 66(8):423-4. PMID: 19593800.
      Citations:    
    7. Katayama H, Sasai K, Kloc M, Brinkley BR, Sen S. Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle. 2008 Sep 01; 7(17):2691-704. PMID: 18773538.
      Citations: 29     Fields:    Translation:HumansCells
    8. Slattery SD, Moore RV, Brinkley BR, Hall RM. Aurora-C and Aurora-B share phosphorylation and regulation of CENP-A and Borealin during mitosis. Cell Cycle. 2008 Mar 15; 7(6):787-95. PMID: 18239465.
      Citations: 23     Fields:    Translation:HumansCells
    9. Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest. 2007 Jul; 117(7):1893-901. PMID: 17607363; PMCID: PMC1904325.
      Citations: 63     Fields:    Translation:AnimalsCells
    10. MacCorkle RA, Slattery SD, Nash DR, Brinkley BR. Intracellular protein binding to asbestos induces aneuploidy in human lung fibroblasts. Cell Motil Cytoskeleton. 2006 Oct; 63(10):646-57. PMID: 16937396.
      Citations:    
    11. Nishino M, Kurasawa Y, Evans R, Lin SH, Brinkley BR, Yu-Lee LY. NudC is required for Plk1 targeting to the kinetochore and chromosome congression. Curr Biol. 2006 Jul 25; 16(14):1414-21. PMID: 16860740.
      Citations: 52     Fields:    Translation:HumansCells
    12. Brinkley BR. Elusive nucleoskeleton visualized in live cells. Cell Motil Cytoskeleton. 2004 Oct; 59(2):119. PMID: 15362115.
      Citations:    
    13. Stenoien DL, Sen S, Mancini MA, Brinkley BR. Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton. 2003 Jun; 55(2):134-46. PMID: 12740874.
      Citations: 33     Fields:    Translation:HumansCells
    14. Ouspenski II, Van Hooser AA, Brinkley BR. Relevance of histone acetylation and replication timing for deposition of centromeric histone CENP-A. Exp Cell Res. 2003 May 01; 285(2):175-88. PMID: 12706113.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    15. Gregson HC, Van Hooser AA, Ball AR, Brinkley BR, Yokomori K. Localization of human SMC1 protein at kinetochores. Chromosome Res. 2002; 10(4):267-77. PMID: 12199140.
      Citations: 6     Fields:    Translation:HumansCells
    16. MacCorkle-Chosnek RA, VanHooser A, Goodrich DW, Brinkley BR, Tan TH. Cell cycle regulation of c-Jun N-terminal kinase activity at the centrosomes. Biochem Biophys Res Commun. 2001 Nov 23; 289(1):173-80. PMID: 11708796.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    17. Zhou G, Mihindukulasuriya KA, MacCorkle-Chosnek RA, Van Hooser A, Hu MC, Brinkley BR, Tan TH. Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase. J Biol Chem. 2002 Feb 22; 277(8):6391-8. PMID: 11698396.
      Citations: 29     Fields:    Translation:HumansCells
    18. Cabello OA, Eliseeva E, He WG, Youssoufian H, Plon SE, Brinkley BR, Belmont JW. Cell cycle-dependent expression and nucleolar localization of hCAP-H. Mol Biol Cell. 2001 Nov; 12(11):3527-37. PMID: 11694586; PMCID: PMC60273.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    19. Van Hooser AA, Ouspenski II, Gregson HC, Starr DA, Yen TJ, Goldberg ML, Yokomori K, Earnshaw WC, Sullivan KF, Brinkley BR. Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J Cell Sci. 2001 Oct; 114(Pt 19):3529-42. PMID: 11682612.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    20. Brinkley BR. Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol. 2001 Jan; 11(1):18-21. PMID: 11146294.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    21. Goepfert TM, McCarthy M, Kittrell FS, Stephens C, Ullrich RL, Brinkley BR, Medina D. Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells. FASEB J. 2000 Nov; 14(14):2221-9. PMID: 11053243.
      Citations: 21     Fields:    Translation:AnimalsCells
    22. Go C, He W, Zhong L, Li P, Huang J, Brinkley BR, Wang XJ. Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII. Oncogene. 2000 Jul 27; 19(32):3623-31. PMID: 10951568.
      Citations: 7     Fields:    Translation:AnimalsCells
    23. Ouspenski II, Cabello OA, Brinkley BR. Chromosome condensation factor Brn1p is required for chromatid separation in mitosis. Mol Biol Cell. 2000 Apr; 11(4):1305-13. PMID: 10749931; PMCID: PMC14848.
      Citations: 50     Fields:    Translation:AnimalsCells
    24. Goepfert TM, Brinkley BR. The centrosome-associated Aurora/Ipl-like kinase family. Curr Top Dev Biol. 2000; 49:331-42. PMID: 11005026.
      Citations: 17     Fields:    Translation:HumansCells
    25. Van Hooser AA, Mancini MA, Allis CD, Sullivan KF, Brinkley BR. The mammalian centromere: structural domains and the attenuation of chromatin modeling. FASEB J. 1999 Dec; 13 Suppl 2:S216-20. PMID: 10619130.
      Citations: 14     Fields:    Translation:AnimalsCells
    26. Ouspenski II, Elledge SJ, Brinkley BR. New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res. 1999 Aug 01; 27(15):3001-8. PMID: 10454593; PMCID: PMC148523.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    27. McNeil RS, Swann JW, Brinkley BR, Clark GD. Neuronal cytoskeletal alterations evoked by a platelet-activating factor (PAF) analogue. Cell Motil Cytoskeleton. 1999; 43(2):99-113. PMID: 10379835.
      Citations: 6     Fields:    Translation:AnimalsCells
    28. Van Hooser A, Goodrich DW, Allis CD, Brinkley BR, Mancini MA. Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J Cell Sci. 1998 Dec; 111 ( Pt 23):3497-506. PMID: 9811564.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    29. Kapoor M, Montes de Oca Luna R, Liu G, Lozano G, Cummings C, Mancini M, Ouspenski I, Brinkley BR, May GS. The cenpB gene is not essential in mice. Chromosoma. 1998 Dec; 107(8):570-6. PMID: 9933410.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    30. Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Brinkley BR, Roop DR. Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function. Mol Carcinog. 1998 Nov; 23(3):185-92. PMID: 9833779.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    31. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet. 1998 Oct; 20(2):189-93. PMID: 9771714.
      Citations: 436     Fields:    Translation:HumansAnimalsCells
    32. Cabello OA, Brinkley BR, Youssoufian H, Belmont JW. Genomic stability and the mechanisms of chromatid separation in mammalian cells. Mol Genet Metab. 1998 Oct; 65(2):105-12. PMID: 9787102.
      Citations:    Fields:    Translation:HumansAnimalsCells
    33. Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 09; 17(1):35-45. PMID: 9671312.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    34. He D, Zeng C, Woods K, Zhong L, Turner D, Busch RK, Brinkley BR, Busch H. CENP-G: a new centromeric protein that is associated with the alpha-1 satellite DNA subfamily. Chromosoma. 1998 Jun; 107(3):189-97. PMID: 9639657.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    35. Brinkley BR, Goepfert TM. Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected. Cell Motil Cytoskeleton. 1998; 41(4):281-8. PMID: 9858153.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    36. Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, Brinkley BR, Bazett-Jones DP, Allis CD. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 1997 Nov; 106(6):348-60. PMID: 9362543.
      Citations: 786     Fields:    Translation:AnimalsCells
    37. Wise DA, Brinkley BR. Mitosis in cells with unreplicated genomes (MUGs): spindle assembly and behavior of centromere fragments. Cell Motil Cytoskeleton. 1997; 36(3):291-302. PMID: 9067624.
      Citations: 27     Fields:    Translation:AnimalsCells
    38. He D, Brinkley BR. Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells. J Cell Sci. 1996 Nov; 109 ( Pt 11):2693-704. PMID: 8937987.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    39. Mancini MA, He D, Ouspenski II, Brinkley BR. Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle. J Cell Biochem. 1996 Aug; 62(2):158-64. PMID: 8844395.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    40. Murti KG, He DC, Brinkley BR, Scott R, Lee SH. Dynamics of human replication protein A subunit distribution and partitioning in the cell cycle. Exp Cell Res. 1996 Mar 15; 223(2):279-89. PMID: 8601405.
      Citations: 23     Fields:    Translation:HumansCells
    41. Balczon R, Bao L, Zimmer WE, Brown K, Zinkowski RP, Brinkley BR. Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells. J Cell Biol. 1995 Jul; 130(1):105-15. PMID: 7790366; PMCID: PMC2120504.
      Citations: 112     Fields:    Translation:AnimalsCells
    42. Ouspenski II, Mueller UW, Matynia A, Sazer S, Elledge SJ, Brinkley BR. Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast. J Biol Chem. 1995 Feb 03; 270(5):1975-8. PMID: 7836422.
      Citations: 25     Fields:    Translation:AnimalsCells
    43. He D, Zeng C, Brinkley BR. Nuclear matrix proteins as structural and functional components of the mitotic apparatus. Int Rev Cytol. 1995; 162B:1-74. PMID: 8557485.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    44. Zeng C, He D, Berget SM, Brinkley BR. Nuclear-mitotic apparatus protein: a structural protein interface between the nucleoskeleton and RNA splicing. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1505-9. PMID: 8108437; PMCID: PMC43188.
      Citations: 21     Fields:    Translation:HumansCells
    45. Zeng C, He D, Brinkley BR. Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells. Cell Motil Cytoskeleton. 1994; 29(2):167-76. PMID: 7820866.
      Citations: 19     Fields:    Translation:HumansCells
    46. Cristiano RJ, Smith LC, Kay MA, Brinkley BR, Woo SL. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11548-52. PMID: 8265587; PMCID: PMC48021.
      Citations: 23     Fields:    Translation:AnimalsCells
    47. Zalensky AO, Breneman JW, Zalenskaya IA, Brinkley BR, Bradbury EM. Organization of centromeres in the decondensed nuclei of mature human sperm. Chromosoma. 1993 Sep; 102(8):509-18. PMID: 8243163.
      Citations: 31     Fields:    Translation:HumansCells
    48. Ouspenski II, Brinkley BR. Centromeric DNA cloned from functional kinetochore fragments in mitotic cells with unreplicated genomes. J Cell Sci. 1993 Jun; 105 ( Pt 2):359-67. PMID: 8408270.
      Citations: 7     Fields:    Translation:AnimalsCells
    49. Brinkley BR, Ouspenski I, Zinkowski RP. Structure and molecular organization of the centromere-kinetochore complex. Trends Cell Biol. 1992 Jan; 2(1):15-21. PMID: 14731633.
      Citations:    
    50. Brinkley BR. Chromosomes, kinetochores and the microtubule connection. Bioessays. 1991 Dec; 13(12):675-81. PMID: 1789785.
      Citations:    Fields:    Translation:HumansAnimalsCells
    51. Ortiz M, Bejarano LA, Rendón MC, Martin G, Brinkley BR, Valdivia MM, Ortiz M, Rend?n MC. Monoclonal antibody with specificity to a conserved epitope in the C-terminal domain of histone H1 variants. Cell Struct Funct. 1991 Aug; 16(4):323-31. PMID: 1723660.
      Citations:    Fields:    Translation:HumansCells
    52. Zinkowski RP, Meyne J, Brinkley BR. The centromere-kinetochore complex: a repeat subunit model. J Cell Biol. 1991 Jun; 113(5):1091-110. PMID: 1828250; PMCID: PMC2289018.
      Citations: 128     Fields:    Translation:HumansAnimalsCells
    53. Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J. 1991 May; 10(5):1245-54. PMID: 2022189; PMCID: PMC452779.
      Citations: 167     Fields:    Translation:HumansCells
    54. Tousson A, Zeng C, Brinkley BR, Valdivia MM. Centrophilin: a novel mitotic spindle protein involved in microtubule nucleation. J Cell Biol. 1991 Feb; 112(3):427-40. PMID: 1991791; PMCID: PMC2288835.
      Citations: 23     Fields:    Translation:HumansCells
    55. Balczon R, Accavitti MA, Brinkley BR. Identification of a 40 x 10(3) Mr centromere-associated protein in cultured mammalian cells. J Cell Sci. 1990 Dec; 97 ( Pt 4):705-13. PMID: 2077041.
      Citations:    Fields:    Translation:HumansAnimalsCells
    56. Simerly C, Balczon R, Brinkley BR, Schatten G. Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes. J Cell Biol. 1990 Oct; 111(4):1491-504. PMID: 2211822; PMCID: PMC2116227.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    57. Brinkley BR. Centromeres and kinetochores: integrated domains on eukaryotic chromosomes. Curr Opin Cell Biol. 1990 Jun; 2(3):446-52. PMID: 2198897.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    58. Mole-Bajer J, Bajer AS, Zinkowski RP, Balczon RD, Brinkley BR. Autoantibodies from a patient with scleroderma CREST recognized kinetochores of the higher plant Haemanthus. Proc Natl Acad Sci U S A. 1990 May; 87(9):3599-603. PMID: 2185478; PMCID: PMC53949.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    59. Zinkowski RP, McCune SL, Balczon RD, Rao PN, Brinkley BR. The centromere and aneuploidy: II. Drug induced detachment and fragmentation of kinetochores of mammalian chromosomes. Prog Clin Biol Res. 1990; 340B:223-36. PMID: 2392445.
      Citations:    Fields:    Translation:AnimalsCells
    60. Brinkley BR. Toward a structural and molecular definition of the kinetochore. Cell Motil Cytoskeleton. 1990; 16(2):104-9. PMID: 2198111.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    61. Balczon RD, Brinkley BR. Synthesis of azidotubulin: a photoaffinity label for tubulin-binding proteins. Biochemistry. 1989 Oct 17; 28(21):8490-6. PMID: 2605199.
      Citations:    Fields:    Translation:AnimalsCells
    62. Tousson A, Alley CD, Sorscher EJ, Brinkley BR, Benos DJ. Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia. J Cell Sci. 1989 Jun; 93 ( Pt 2):349-62. PMID: 2559094.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    63. Zinkowski RP, McCune SL, Balczon RD, Rao PN, Brinkley BR. The centromere and aneuploidy: I. Caffeine-induced detachment and fragmentation of kinetochores of mammalian chromosomes. Prog Clin Biol Res. 1989; 318:43-60. PMID: 2696977.
      Citations: 1     Fields:    Translation:AnimalsCells
    64. Brinkley BR, Zinkowski RP, Mollon WL, Davis FM, Pisegna MA, Pershouse M, Rao PN. Movement and segregation of kinetochores experimentally detached from mammalian chromosomes. Nature. 1988 Nov 17; 336(6196):251-4. PMID: 3057382.
      Citations: 55     Fields:    Translation:AnimalsCells
    65. Lai CN, Gallick GE, Maxwell SA, Brinkley BR, Becker FF. Potassium inhibition of transforming protein P85gag-mos and reversal of the transformed phenotype in 6m2 cells. J Cell Physiol. 1988 Mar; 134(3):445-52. PMID: 2965157.
      Citations: 1     Fields:    Translation:AnimalsCells
    66. Balczon RD, Brinkley BR. Tubulin interaction with kinetochore proteins: analysis by in vitro assembly and chemical cross-linking. J Cell Biol. 1987 Aug; 105(2):855-62. PMID: 3305522; PMCID: PMC2114760.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    67. Wood CM, Timme TL, Hurt MM, Brinkley BR, Ledbetter DH, Moses RE. Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid. Exp Cell Res. 1987 Apr; 169(2):543-53. PMID: 3030788.
      Citations: 1     Fields:    Translation:HumansCells
    68. Wheeler WJ, Hsu TC, Tousson A, Brinkley BR. Mitotic inhibition and chromosome displacement induced by estradiol in Chinese hamster cells. Cell Motil Cytoskeleton. 1987; 7(3):235-47. PMID: 3594578.
      Citations: 4     Fields:    Translation:AnimalsCells
    69. Perry G, Wible L, Brinkley BR. Microtubules are not altered in the dystrophic chicken. Exp Cell Res. 1986 Mar; 163(1):266-72. PMID: 3510888.
      Citations:    Fields:    Translation:AnimalsCells
    70. Valdivia MM, Tousson A, Brinkley BR. Human antibodies and their use for the study of chromosome organization. Methods Achiev Exp Pathol. 1986; 12:200-23. PMID: 3515123.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    71. Brinkley BR, Brenner SL, Hall JM, Tousson A, Balczon RD, Valdivia MM. Arrangements of kinetochores in mouse cells during meiosis and spermiogenesis. Chromosoma. 1986; 94(4):309-17. PMID: 3539554.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    72. Valdivia MM, Brinkley BR. Isolation of a kinetochore-centromere fraction from HeLa metaphase chromosomes. Methods Enzymol. 1986; 134:268-80. PMID: 3547036.
      Citations: 1     Fields:    Translation:HumansCells
    73. Valdivia MM, Brinkley BR. Fractionation and initial characterization of the kinetochore from mammalian metaphase chromosomes. J Cell Biol. 1985 Sep; 101(3):1124-34. PMID: 3897244; PMCID: PMC2113728.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    74. Merry DE, Pathak S, Hsu TC, Brinkley BR. Anti-kinetochore antibodies: use as probes for inactive centromeres. Am J Hum Genet. 1985 Mar; 37(2):425-30. PMID: 3885726; PMCID: PMC1684577.
      Citations: 31     Fields:    Translation:HumansCells
    75. Nielsen TB, Ferdows MS, Brinkley BR, Field JB. Morphological and biochemical responses of cultured thyroid cells to thyrotropin. Endocrinology. 1985 Feb; 116(2):788-97. PMID: 2578386.
      Citations: 4     Fields:    Translation:AnimalsCells
    76. Brinkley BR. Microtubule organizing centers. Annu Rev Cell Biol. 1985; 1:145-72. PMID: 3916316.
      Citations: 102     Fields:    Translation:AnimalsCells
    77. Brinkley BR, Tousson A, Valdivia MM. The kinetochore of mammalian chromosomes: structure and function in normal mitosis and aneuploidy. Basic Life Sci. 1985; 36:243-67. PMID: 3913415.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    78. Liang JC, Brinkley BR. Chemical probes and possible targets for the induction of aneuploidy. Basic Life Sci. 1985; 36:491-505. PMID: 4096703.
      Citations:    Fields:    Translation:AnimalsCells
    79. Anderson DC, Schmalstieg FC, Arnaout MA, Kohl S, Tosi MF, Dana N, Buffone GJ, Hughes BJ, Brinkley BR, Dickey WD, et al. Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence. J Clin Invest. 1984 Aug; 74(2):536-51. PMID: 6746906; PMCID: PMC370506.
      Citations: 64     Fields:    Translation:HumansCells
    80. Anderson DC, Hughes BJ, Wible LJ, Perry GJ, Smith CW, Brinkley BR. Impaired motility of neonatal PMN leukocytes: relationship to abnormalities of cell orientation and assembly of microtubules in chemotactic gradients. J Leukoc Biol. 1984 Jul; 36(1):1-15. PMID: 6376671.
      Citations: 5     Fields:    Translation:HumansCells
    81. Deery WJ, Means AR, Brinkley BR. Calmodulin-microtubule association in cultured mammalian cells. J Cell Biol. 1984 Mar; 98(3):904-10. PMID: 6365929; PMCID: PMC2113150.
      Citations: 17     Fields:    Translation:AnimalsCells
    82. Eckert BS, Caputi SE, Brinkley BR. Localization of the centriole and keratin intermediate filaments in PtK1 cells by double immunofluorescence. Cell Motil. 1984; 4(4):241-7. PMID: 6206954.
      Citations:    Fields:    Translation:Cells
    83. Brinkley BR, Valdivia MM, Tousson A, Brenner SL. Compound kinetochores of the Indian muntjac. Evolution by linear fusion of unit kinetochores. Chromosoma. 1984; 91(1):1-11. PMID: 6525895.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    84. Cabral F, Wible L, Brenner S, Brinkley BR. Taxol-requiring mutant of Chinese hamster ovary cells with impaired mitotic spindle assembly. J Cell Biol. 1983 Jul; 97(1):30-9. PMID: 6134737; PMCID: PMC2112497.
      Citations: 15     Fields:    Translation:AnimalsCells
    85. Deery WJ, Brinkley BR. Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model. J Cell Biol. 1983 Jun; 96(6):1631-41. PMID: 6304113; PMCID: PMC2112452.
      Citations: 4     Fields:    Translation:AnimalsCells
    86. Beall PT, Brinkley BR, Chang DC, Hazlewood CF. Microtubule complexes correlated with growth rate and water proton relaxation times in human breast cancer cells. Cancer Res. 1982 Oct; 42(10):4124-30. PMID: 7049356.
      Citations: 1     Fields:    Translation:HumansCells
    87. Brinkley BR. The cytoskeleton: a perspective. Methods Cell Biol. 1982; 24:1-8. PMID: 7201561.
      Citations: 2     Fields:    Translation:AnimalsCells
    88. Brenner SL, Brinkley BR. Tubulin assembly sites and the organization of microtubule arrays in mammalian cells. Cold Spring Harb Symp Quant Biol. 1982; 46 Pt 1:241-54. PMID: 6125294.
      Citations: 7     Fields:    Translation:AnimalsCells
    89. Zimmer DB, Turner DS, Goldstein MA, Brinkley BR. A quantitative ultrastructural study of microtubules in transformed and nontransformed cells in vitro. Cell Biol Int Rep. 1981 Dec; 5(12):1115-25. PMID: 7326754.
      Citations:    Fields:    Translation:AnimalsCells
    90. Brenner S, Pepper D, Berns MW, Tan E, Brinkley BR. Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients. J Cell Biol. 1981 Oct; 91(1):95-102. PMID: 7298727; PMCID: PMC2111947.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    91. Brown RL, Horn JP, Wible L, Arlinghaus RB, Brinkley BR. Sequence of events in the transformation process in cells infected with a temperature-sensitive transformation mutant of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A. 1981 Sep; 78(9):5593-7. PMID: 6946495; PMCID: PMC348797.
      Citations: 11     Fields:    Translation:AnimalsCells
    92. Brinkley BR, Cox SM, Pepper DA, Wible L, Brenner SL, Pardue RL. Tubulin assembly sites and the organization of cytoplasmic microtubules in cultured mammalian cells. J Cell Biol. 1981 Sep; 90(3):554-62. PMID: 7026576; PMCID: PMC2111901.
      Citations: 37     Fields:    Translation:AnimalsCells
    93. Pardue RL, Kaetzel MA, Hahn SH, Brinkley BR, Dedman JR. The identification of calmodulin-binding sites on mitochondria in cultured 3T3 cells. Cell. 1981 Feb; 23(2):533-42. PMID: 7193532.
      Citations: 6     Fields:    Translation:AnimalsCells
    94. Chafouleas JG, Pardue RL, Brinkley BR, Dedman JR, Means AR. Regulation of intracellular levels of calmodulin and tubulin in normal and transformed cells. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):996-1000. PMID: 6262788; PMCID: PMC319932.
      Citations: 37     Fields:    Translation:AnimalsCells
    95. Lasek RJ, Solomon F, Brinkley BR. Which cytoskeletal determinants preserve ontogenetic history? Neurosci Res Program Bull. 1981 Feb; 19(1):125-35. PMID: 7193815.
      Citations:    Fields:    Translation:HumansAnimalsCells
    96. Brinkley BR, Beall PT, Wible LJ, Mace ML, Turner DS, Cailleau RM. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. Cancer Res. 1980 Sep; 40(9):3118-29. PMID: 7000337.
      Citations: 68     Fields:    Translation:HumansCells
    97. Asch BB, Medina D, Kretzer F, Connolly JL, Brinkley BR. Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties. Cancer Res. 1980 Jul; 40(7):2383-9. PMID: 6248204.
      Citations: 1     Fields:    Translation:AnimalsCells
    98. Brown RL, Wible LJ, Brinkley BR. Cytoplasmic microtubule assembly-disassembly in enucleated cells and regenerating karyoplasts. Cell Biol Int Rep. 1980 May; 4(5):453-8. PMID: 6156770.
      Citations: 2     Fields:    Translation:AnimalsCells
    99. Brinkley BR, Cox SM, Pepper DA. Structure of the mitotic apparatus and chromosomes after hypotonic treatment of mammalian cells in vitro. Cytogenet Cell Genet. 1980; 26(2-4):165-74. PMID: 6993107.
      Citations: 11     Fields:    Translation:AnimalsCells
    100. Brinkley BR, Wible LJ, Asch BB, Medina D, Mace MM, Beall PT, Cailleau RM. The microtubule cytoskeleton in normal and transformed cells in vitro. Results Probl Cell Differ. 1980; 11:132-8. PMID: 7003669.
      Citations: 1     Fields:    Translation:AnimalsCells
    101. Pepper DA, Brinkley BR. Tubulin nucleation and assembly in mitotic cells: evidence for nucleic acids in kinetochores and centrosomes. Cell Motil. 1980; 1(1):1-15. PMID: 6184168.
      Citations: 19     Fields:    Translation:AnimalsCells
    102. Brinkley BR, Fistel SH, Marcum JM, Pardue RL. Microtubules in cultured cells; indirect immunofluorescent staining with tubulin antibody. Int Rev Cytol. 1980; 63:59-95. PMID: 395133.
      Citations: 35     Fields:    Translation:AnimalsCells
    103. Pepper DA, Brinkley BR. Microtubule initiation at kinetochores and centrosomes in lysed mitotic cells. Inhibition of site-specific nucleation by tubulin antibody. J Cell Biol. 1979 Aug; 82(2):585-91. PMID: 479317; PMCID: PMC2110471.
      Citations: 22     Fields:    Translation:AnimalsCells
    104. Welsh MJ, Dedman JR, Brinkley BR, Means AR. Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. J Cell Biol. 1979 Jun; 81(3):624-34. PMID: 379022; PMCID: PMC2110392.
      Citations: 56     Fields:    Translation:AnimalsCells
    105. Asch BB, Medina D, Brinkley BR. Microtubules and actin-containing filaments of normal, preneoplastic, and neoplastic mouse mammary epithelial cells. Cancer Res. 1979 Mar; 39(3):893-907. PMID: 371792.
      Citations: 8     Fields:    Translation:AnimalsCells
    106. Sunkara PS, Rao PN, Nishioka K, Brinkley BR. Role of polyamines in cytokinesis of mammalian cells. Exp Cell Res. 1979 Mar 01; 119(1):63-8. PMID: 570113.
      Citations: 5     Fields:    Translation:Cells
    107. Nicklas RB, Brinkley BR, Pepper DA, Kubai DF, Rickards GK. Electron microscopy of spermatocytes previously studied in life: methods and some observations on micromanipulated chromosomes. J Cell Sci. 1979 Feb; 35:87-104. PMID: 370131.
      Citations: 34     Fields:    Translation:AnimalsCells
    108. Dedman JR, Brinkley BR, Means AR. Regulation of microfilaments and microtubules by calcium and cyclic AMP. Adv Cyclic Nucleotide Res. 1979; 11:131-74. PMID: 227246.
      Citations: 35     Fields:    Translation:AnimalsCells
    109. Brinkley BR, Cox SM. Double fluorescent staining for the separate demonstration of chromosomes and microtubules in mitotic cells in vitro. Stain Technol. 1978 Nov; 53(6):345-9. PMID: 89722.
      Citations: 1     Fields:    Translation:Cells
    110. Marcum JM, Dedman JR, Brinkley BR, Means AR. Control of microtubule assembly-disassembly by calcium-dependent regulator protein. Proc Natl Acad Sci U S A. 1978 Aug; 75(8):3771-5. PMID: 211505; PMCID: PMC392868.
      Citations: 104     Fields:    Translation:AnimalsCells
    111. Welsh MJ, Dedman JR, Brinkley BR, Means AR. Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. Proc Natl Acad Sci U S A. 1978 Apr; 75(4):1867-71. PMID: 273915; PMCID: PMC392442.
      Citations: 66     Fields:    Translation:Cells
    112. Brinkley BR, Fuller GM. Tubulin and actin immunofluorescence as an aid in detecting cell transformation in vitro. Tex Rep Biol Med. 1978; 37:26-44. PMID: 380045.
      Citations:    Fields:    Translation:HumansAnimalsCells
    113. Miller CL, Fuseler JW, Brinkley BR. Cytoplasmic microtubules in transformed mouse x nontransformed human cell hybrids: correlation with in vitro growth. Cell. 1977 Sep; 12(1):319-31. PMID: 332382.
      Citations: 9     Fields:    Translation:Cells
    114. Pepper DA, Brinkley BR. Localization of tubulin in the mitotic apparatus of mammalian cells by immunofluorescence and immunoelectron microscopy. Chromosoma. 1977 Apr 19; 60(3):223-35. PMID: 322970.
      Citations: 16     Fields:    Translation:Cells
    115. McGill M, Highfield DP, Monahan TM, Brinkley BR. Effects of nucleic acid specific dyes on centrioles of mammalian cells. J Ultrastruct Res. 1976 Oct; 57(1):43-53. PMID: 978782.
      Citations: 1     Fields:    Translation:Cells
    116. Barham SS, Brinkley BR. Action of rotenone and related respiratory inhibitors on mammalian cell division. 1 Cell kinetics and biochemical aspects. Cytobios. 1976; 15(58-59):85-96. PMID: 1001024.
      Citations: 2     Fields:    Translation:Cells
    117. Barham SS, Brinkley BR. Action of rotenone and related respiratory inhibitors on mammalian cell division. 2 Ultrastructural studies. Cytobios. 1976; 15(58-59):97-109. PMID: 1001025.
      Citations: 3     Fields:    Translation:Cells
    118. Fuller GM, Brinkley BR. Structure and control of assembly of cytoplasmic microtubules in normal and transformed cells. J Supramol Struct. 1976; 5(4):497(349)-514(366). PMID: 800619.
      Citations: 24     Fields:    Translation:Cells
    119. Brinkley BR, Fuller EM, Highfield DP. Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence. Proc Natl Acad Sci U S A. 1975 Dec; 72(12):4981-5. PMID: 174086; PMCID: PMC388858.
      Citations: 93     Fields:    Translation:Cells
    120. McGill M, Brinkley BR. Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin. J Cell Biol. 1975 Oct; 67(1):189-99. PMID: 809450; PMCID: PMC2109587.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    121. Brinkley BR, Cartwright J. Cold-labile and cold-stable microtubules in the mitotic spindle of mammalian cells. Ann N Y Acad Sci. 1975 Jun 30; 253:428-39. PMID: 1056753.
      Citations: 90     Fields:    Translation:AnimalsCells
    122. Fuller GM, Brinkley BR, Boughter JM. Immunofluorescence of mitotic spindles by using monospecific antibody against bovine brain tubulin. Science. 1975 Mar 14; 187(4180):948-50. PMID: 1096300.
      Citations: 67     Fields:    Translation:AnimalsCells
    123. Brinkley BR, Hittelman WN. Ultrastructure of mammalian chromosome aberrations. Int Rev Cytol. 1975; 42:49-101. PMID: 53216.
      Citations: 5     Fields:    Translation:AnimalsCells
    124. Brinkley BR, Barham SS, Barranco SC, Fuller GM. Rotenone inhibition of spindle microtubule assembly in mammalian cells. Exp Cell Res. 1974 Mar 30; 85(1):41-6. PMID: 4857086.
      Citations: 43     Fields:    Translation:AnimalsCells
    125. Brinkley BR, Rao PN. Nitrous oxide: effects on the mitotic apparatus and chromosome movement in HeLa cells. J Cell Biol. 1973 Jul; 58(1):96-106. PMID: 4726309; PMCID: PMC2109015.
      Citations: 9     Fields:    Translation:HumansCells
    126. Mace ML, Tevethia SS, Brinkley BR. Differential immunofluorescent labeling of chromosomes with antisera specific for single strand DNA. Exp Cell Res. 1972 Dec; 75(2):521-3. PMID: 4566307.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    127. Rattner JB, Brinkley BR. Ultrastructure of mammalian spermiogenesis. 3. The organization and morphogenesis of the manchette during rodent spermiogenesis. J Ultrastruct Res. 1972 Nov; 41(3):209-18. PMID: 4636018.
      Citations: 12     Fields:    Translation:AnimalsCells
    128. Brinkley BR, Cartwright J. Ultrastructural analysis of mitotic spindle elongation in mammalian cells in vitro. Direct microtubule counts. J Cell Biol. 1971 Aug; 50(2):416-31. PMID: 4939523; PMCID: PMC2108283.
      Citations: 68     Fields:    Translation:AnimalsCells
    129. Rattner JB, Brinkley BR. Ultrastructure of mammalian spermiogenesis. II. Elimination of the nuclear membrane. J Ultrastruct Res. 1971 Jul; 36(1):1-7. PMID: 4998636.
      Citations: 2     Fields:    Translation:AnimalsCells
    130. Hsu TC, Cooper JE, Mace ML, Brinkley BR. Arrangement of centromeres in mouse cells. Chromosoma. 1971; 34(1):73-87. PMID: 4105528.
      Citations: 89     Fields:    Translation:AnimalsCells
    131. Humphrey RM, Brinkley BR. Ultrastructural studies of radiation-induced chromosome damage. J Cell Biol. 1969 Sep; 42(3):745-53. PMID: 4895598; PMCID: PMC2107714.
      Citations: 6     Fields:    Translation:AnimalsCells
    132. Brinkley BR, Stubblefield E, Hsu TC. The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro. J Ultrastruct Res. 1967 Jul; 19(1):1-18. PMID: 5339063.
      Citations: 65     Fields:    Translation:AnimalsCells
    133. Hsu TC, Brinkley BR, Arrighi FE. The structure and behavior of the nucleolus organizer in mammalian cells. Chromosoma. 1967; 23(2):137-53. PMID: 4970485.
      Citations: 28     Fields:    Translation:AnimalsCells
    134. Stubblefield E, Brinkley BR. Cilia formation in Chinese hamster fibroblasts in vitro as a response to colcemid treatment. J Cell Biol. 1966 Sep; 30(3):645-52. PMID: 5971010; PMCID: PMC2107012.
      Citations: 34     Fields:    Translation:AnimalsCells
    135. Brinkley BR, Stubblefield E. The fine structure of the kinetochore of a mammalian cell in vitro. Chromosoma. 1966; 19(1):28-43. PMID: 5912064.
      Citations: 84     Fields:    Translation:AnimalsCells
    136. Brinkley BR. The fine structure of the nucleolus in mitotic divisions of Chinese hamster cells in vitro. J Cell Biol. 1965 Nov; 27(2):411-22. PMID: 5884631; PMCID: PMC2106730.
      Citations: 16     Fields:    Translation:AnimalsCells
    137. Hsu TC, Arrighi FE, Klevecz RR, Brinkley BR. The nucleoli in mitotic divisions of mammalian cells in vitro. J Cell Biol. 1965 Aug; 26(2):539-53. PMID: 4222282; PMCID: PMC2106756.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
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