"Muscimol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
| Descriptor ID |
D009118
|
| MeSH Number(s) |
D03.383.129.462.470 D23.946.587.587
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscimol".
Below are MeSH descriptors whose meaning is more specific than "Muscimol".
This graph shows the total number of publications written about "Muscimol" by people in this website by year, and whether "Muscimol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Muscimol" by people in Profiles.
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Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons through NKCC1 Upregulation. Neuroendocrinology. 2017; 104(2):194-208.
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Evidence for a Causal Contribution of Macaque Vestibular, But Not Intraparietal, Cortex to Heading Perception. J Neurosci. 2016 Mar 30; 36(13):3789-98.
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Causal evidence of performance monitoring by neurons in posterior cingulate cortex during learning. Neuron. 2013 Dec 18; 80(6):1384-91.
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GABAC receptor binding of quantum-dot conjugates of variable ligand valency. Bioconjug Chem. 2010 Aug 18; 21(8):1455-64.
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Medial prefrontal cortical activation modulates the impact of controllable and uncontrollable stressor exposure on a social exploration test of anxiety in the rat. Stress. 2009 Sep; 12(5):445-50.
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Stimulation of alpha(1)-adrenoceptors reduces glutamatergic synaptic input from primary afferents through GABA(A) receptors and T-type Ca(2+) channels. Neuroscience. 2009 Feb 18; 158(4):1616-24.
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Binding of muscimol-conjugated quantum dots to GABAC receptors. J Am Chem Soc. 2006 Dec 13; 128(49):15701-13.
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Role of gamma-aminobutyric acid (GABA)A and GABAB receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension. J Pharmacol Exp Ther. 2007 Feb; 320(2):615-26.
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Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis. Psychopharmacology (Berl). 2006 May; 185(4):423-32.
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Pavlovian fear memory induced by activation in the anterior cingulate cortex. Mol Pain. 2005 Feb 09; 1:6.