"Gliotoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal toxin produced by various species of Trichoderma, Gladiocladium fimbriatum, Aspergillus fumigatus, and Penicillium. It is used as an immunosuppressive agent.
| Descriptor ID |
D005912
|
| MeSH Number(s) |
D03.633.100.473.360 D23.946.587.401
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Gliotoxin".
Below are MeSH descriptors whose meaning is more specific than "Gliotoxin".
This graph shows the total number of publications written about "Gliotoxin" by people in this website by year, and whether "Gliotoxin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gliotoxin" by people in Profiles.
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Diketopiperazine Formation in Fungi Requires Dedicated Cyclization and Thiolation Domains. Angew Chem Int Ed Engl. 2019 10 07; 58(41):14589-14593.
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Host immune status-specific production of gliotoxin and bis-methyl-gliotoxin during invasive aspergillosis in mice. Sci Rep. 2017 09 08; 7(1):10977.
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Enemy of the (immunosuppressed) state: an update on the pathogenesis of Aspergillus fumigatus infection. Br J Haematol. 2010 Aug; 150(4):406-17.
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Manipulation of host angioneogenesis: A critical link for understanding the pathogenesis of invasive mold infections? Virulence. 2010 May-Jun; 1(3):192-6.
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Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites. Blood. 2009 Dec 17; 114(26):5393-9.
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Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence. J Infect Dis. 2008 Feb 01; 197(3):479-86.
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Genomewide screening for genes associated with gliotoxin resistance and sensitivity in Saccharomyces cerevisiae. Antimicrob Agents Chemother. 2008 Apr; 52(4):1325-9.
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Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center. J Clin Microbiol. 2005 Dec; 43(12):6120-2.
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Detection of gliotoxin in experimental and human aspergillosis. Infect Immun. 2005 Jan; 73(1):635-7.
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Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes. Blood. 2005 Mar 15; 105(6):2258-65.