"Indican" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A substance occurring in the urine of mammals and also in blood plasma as the normal metabolite of tryptophan. An increased urinary excretion of indican is seen in Hartnup disease from the bacterial degradation of unabsorbed tryptophan.
| Descriptor ID |
D007200
|
| MeSH Number(s) |
D03.633.100.473.393
|
| Concept/Terms |
Indican- Indican
- Indoxyl Sulfate
- Sulfate, Indoxyl
- 1H-Indol-3-ol Hydrogen Sulfate Ester
|
Below are MeSH descriptors whose meaning is more general than "Indican".
Below are MeSH descriptors whose meaning is more specific than "Indican".
This graph shows the total number of publications written about "Indican" by people in this website by year, and whether "Indican" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Indican" by people in Profiles.
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Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease. J Clin Invest. 2022 01 04; 132(1).
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Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD. J Am Soc Nephrol. 2021 11; 32(11):2834-2850.
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Microbiota-Mediated Immune Regulation in Atherosclerosis. Molecules. 2021 Jan 01; 26(1).
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Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease. Kidney Int. 2020 03; 97(3):538-550.
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Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 03; 29(3):1063-1072.
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Serum metabolomic profiling and incident CKD among African Americans. Clin J Am Soc Nephrol. 2014 Aug 07; 9(8):1410-7.
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Purple urine bag syndrome in a patient with a nephrostomy tube. N Z Med J. 2010 Apr 09; 123(1312):68-70.
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Purple urine bag syndrome. Am J Emerg Med. 2005 Jul; 23(4):521-4.