Aromatic-L-Amino-Acid Decarboxylases
"Aromatic-L-Amino-Acid Decarboxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme group with broad specificity. The enzymes decarboxylate a range of aromatic amino acids including dihydroxyphenylalanine (DOPA DECARBOXYLASE); TRYPTOPHAN; and HYDROXYTRYPTOPHAN.
| Descriptor ID |
D001142
|
| MeSH Number(s) |
D08.811.520.224.125.100
|
| Concept/Terms |
Aromatic-L-Amino-Acid Decarboxylases- Aromatic-L-Amino-Acid Decarboxylases
- Aromatic L Amino Acid Decarboxylases
- Decarboxylases, Aromatic-L-Amino-Acid
- 5-HTPase
- 5 HTPase
- Hydroxytryptophan Decarboxylase
- Decarboxylase, Hydroxytryptophan
- Amino Acid Decarboxylases, Aromatic
- Aromatic Amino Acid Decarboxylases
- Aromatic-L-Amino-Acid Decarboxylase
- Aromatic L Amino Acid Decarboxylase
- Decarboxylase, Aromatic-L-Amino-Acid
- Tryptophan Decarboxylase
- Decarboxylase, Tryptophan
- 5-Hydroxytryptophan Decarboxylase
- 5 Hydroxytryptophan Decarboxylase
- Decarboxylase, 5-Hydroxytryptophan
|
Below are MeSH descriptors whose meaning is more general than "Aromatic-L-Amino-Acid Decarboxylases".
Below are MeSH descriptors whose meaning is more specific than "Aromatic-L-Amino-Acid Decarboxylases".
This graph shows the total number of publications written about "Aromatic-L-Amino-Acid Decarboxylases" by people in this website by year, and whether "Aromatic-L-Amino-Acid Decarboxylases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aromatic-L-Amino-Acid Decarboxylases" by people in Profiles.
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Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes. Mol Genet Metab. 2023 07; 139(3):107624.
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Spectrum of DDC variants causing aromatic l-amino acid decarboxylase (AADC) deficiency and pathogenicity interpretation using ACMG-AMP/ACGS recommendations. Mol Genet Metab. 2022 Dec; 137(4):359-381.
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Gene therapy improves motor and mental function of aromatic l-amino acid decarboxylase deficiency. Brain. 2019 02 01; 142(2):322-333.
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Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations. Pediatr Neurol. 2017 Oct; 75:66-72.
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A female case of aromatic l-amino acid decarboxylase deficiency responsive to MAO-B inhibition. Brain Dev. 2016 Nov; 38(10):959-963.
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Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma. Mol Genet Metab. 2015 Jun-Jul; 115(2-3):91-4.
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Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells. J Neurosci. 2006 Jun 07; 26(23):6124-30.
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Dopaminergic differentiation of human embryonic stem cells. Stem Cells. 2004; 22(6):925-40.
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Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. Eur J Neurosci. 2003 Oct; 18(7):1731-8.
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Developmental regulation of neurotransmitter phenotype through tetrahydrobiopterin. J Neurosci. 2002 Nov 01; 22(21):9445-52.