"Phospholipase C beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide phospholipase C subtype that is primarily regulated by its association with HETEROTRIMERIC G-PROTEINS. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of C-terminal extension of 400 residues.
| Descriptor ID |
D054799
|
| MeSH Number(s) |
D08.811.277.352.640.700.700.562.500 D12.644.360.571.500 D12.776.476.556.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phospholipase C beta".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase C beta".
This graph shows the total number of publications written about "Phospholipase C beta" by people in this website by year, and whether "Phospholipase C beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phospholipase C beta" by people in Profiles.
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Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020 12; 52(12):1314-1332.
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Targeting Brain-Adaptive Cancer Stem Cells Prohibits Brain Metastatic Colonization of Triple-Negative Breast Cancer. Cancer Res. 2018 04 15; 78(8):2052-2064.
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The heterotrimeric G protein G?1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets. J Biol Chem. 2017 08 11; 292(32):13133-13142.
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G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration. Ann Neurol. 2013 May; 73(5):667-78.
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Neurofilament heavy chain expression reveals a unique parasagittal stripe topography in the mouse cerebellum. Cerebellum. 2011 Sep; 10(3):409-21.
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Subtype-specific role of phospholipase C-beta in bradykinin and LPA signaling through differential binding of different PDZ scaffold proteins. Cell Signal. 2010 Jul; 22(7):1153-61.
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Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 2009 Sep 01; 162(3):574-88.
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Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum. J Neurosci. 2008 Nov 19; 28(47):12150-62.
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Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway. J Biol Chem. 2009 Jan 16; 284(3):1612-9.
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Signal transduction pathways mediating CCK-induced gallbladder muscle contraction. Am J Physiol. 1998 08; 275(2):G203-11.