"Type C Phospholipases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
| Descriptor ID |
D010738
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| MeSH Number(s) |
D08.811.277.352.640.700.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Type C Phospholipases".
Below are MeSH descriptors whose meaning is more specific than "Type C Phospholipases".
This graph shows the total number of publications written about "Type C Phospholipases" by people in this website by year, and whether "Type C Phospholipases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Type C Phospholipases" by people in Profiles.
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Genetic variants related to successful migraine prophylaxis with verapamil. Mol Genet Genomic Med. 2021 06; 9(6):e1680.
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Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24; 289(43):29961-74.
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Activation of nuclear factor ?B (NF-?B) in prostate cancer is mediated by protein kinase C epsilon (PKCepsilon). J Biol Chem. 2012 Oct 26; 287(44):37570-82.
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Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors. J Pharmacol Exp Ther. 2008 May; 325(2):544-55.
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Protease-activated receptor-induced Akt activation--regulation and possible function. J Thromb Haemost. 2007 Dec; 5(12):2484-93.
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Adaptive functional differentiation of dendritic cells: integrating the network of extra- and intracellular signals. Blood. 2006 Jun 15; 107(12):4763-9.
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Gene expression profiling and analysis of signaling pathways involved in priming and differentiation of human neural stem cells. Neuroscience. 2006; 138(1):133-48.
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HIP-55 is important for T-cell proliferation, cytokine production, and immune responses. Mol Cell Biol. 2005 Aug; 25(16):6869-78.
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Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Res. 2004 Jul 15; 64(14):4875-86.
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Calcium signalling in lymphocytes. Curr Opin Immunol. 2003 Jun; 15(3):299-307.