"Phospholipase D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyzes transphosphatidylation reactions. EC 3.1.4.4.
| Descriptor ID |
D010739
|
| MeSH Number(s) |
D08.811.277.352.640.700.710
|
| Concept/Terms |
Phospholipase D- Phospholipase D
- Lecithinase D
- Phosphatidylcholine Phosphohydrolase
|
Below are MeSH descriptors whose meaning is more general than "Phospholipase D".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase D".
This graph shows the total number of publications written about "Phospholipase D" by people in this website by year, and whether "Phospholipase D" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Phospholipase D" by people in Profiles.
-
Clinical activity of programmed cell death 1 (PD-1) blockade in never, light,?and heavy smokers with non-small-cell lung cancer and PD-L1 expression =50. Ann Oncol. 2020 03; 31(3):404-411.
-
Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Dev Cell. 2017 10 23; 43(2):186-197.e7.
-
Phospholipase D1-regulated autophagy supplies free fatty acids to counter nutrient stress in cancer cells. Cell Death Dis. 2016 11 03; 7(11):e2448.
-
PLD3 variants in population studies. Nature. 2015 Apr 02; 520(7545):E2-3.
-
Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Aug; 34(8):1697-703.
-
Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1. J Lipid Res. 2013 Feb; 54(2):379-85.
-
Morphoproteomic analysis reveals an overexpressed and constitutively activated phospholipase D1-mTORC2 pathway in endometrial carcinoma. Int J Clin Exp Pathol. 2010 Nov 20; 4(1):13-21.
-
The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age. J Appl Physiol (1985). 2010 Nov; 109(5):1448-54.
-
Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications. Int J Clin Exp Pathol. 2010 Jan 28; 4(2):134-46.
-
Hydrogen peroxide-induced VCAM-1 expression in pancreatic islets and beta-cells through extracellular Ca2+ influx. Transplantation. 2008 Nov 15; 86(9):1257-66.