"Methylnitrosourea" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
| Descriptor ID |
D008770
|
| MeSH Number(s) |
D02.654.692.480 D02.948.594.490
|
| Concept/Terms |
Methylnitrosourea- Methylnitrosourea
- Nitrosomethylurea
- N-Methyl-N-nitrosourea
- N Methyl N nitrosourea
|
Below are MeSH descriptors whose meaning is more general than "Methylnitrosourea".
Below are MeSH descriptors whose meaning is more specific than "Methylnitrosourea".
This graph shows the total number of publications written about "Methylnitrosourea" by people in this website by year, and whether "Methylnitrosourea" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylnitrosourea" by people in Profiles.
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Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology. 2012 Mar; 142(3):531-42.
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Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats. BMC Cancer. 2009 Jul 29; 9:259.
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Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Invest Ophthalmol Vis Sci. 2007 Jun; 48(6):2799-805.
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Loss of chromosomal integrity drives rat mammary tumorigenesis. Int J Cancer. 2007 Mar 01; 120(5):985-94.
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Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat. 2002 May; 73(1):75-83.
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Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Mol Carcinog. 2002 Jan; 33(1):56-65.
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Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci. 2001 Dec; 952:23-35.
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Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res. 2001 Oct 15; 61(20):7456-63.
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Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. J Endocrinol. 2001 Oct; 171(1):75-83.
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Role of N-methyl-N-nitrosourea in the induction of intestinal metaplasia and gastric adenocarcinoma in Mongolian gerbils infected with Helicobacter pylori. Scand J Gastroenterol. 2001 Mar; 36(3):283-90.