"Acetylcholinesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
| Descriptor ID |
D000110
|
| MeSH Number(s) |
D08.811.277.352.100.170.176
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acetylcholinesterase".
Below are MeSH descriptors whose meaning is more specific than "Acetylcholinesterase".
This graph shows the total number of publications written about "Acetylcholinesterase" by people in this website by year, and whether "Acetylcholinesterase" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylcholinesterase" by people in Profiles.
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4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase. ACS Chem Neurosci. 2024 05 01; 15(9):1813-1827.
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Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation. Biomed Pharmacother. 2024 May; 174:116484.
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Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors. Drug Dev Res. 2022 12; 83(8):1791-1802.
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Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia. Drugs Aging. 2021 07; 38(7):593-602.
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Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study. Drugs Aging. 2021 06; 38(6):493-502.
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Single exercise stress reduces central neurotrophins levels and adenosine A1 and A2 receptors expression, but does not revert opioid-induced hyperalgesia in rats. Int J Dev Neurosci. 2020 Nov; 80(7):636-647.
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Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur J Med Chem. 2020 Dec 01; 207:112761.
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Entomological status of Anopheles sergentii and the first molecular investigation of its insecticide-resistant genes, kdr and ace-1 in Morocco. J Vector Borne Dis. 2019 Oct-Dec; 56(4):308-314.
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Maternal caffeine exposure alters neuromotor development and hippocampus acetylcholinesterase activity in rat offspring. Brain Res. 2015 Jan 21; 1595:10-8.
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Development of myelination and cholinergic innervation in the central auditory system of a prosimian primate (Otolemur garnetti). J Comp Neurol. 2013 Nov; 521(16):3804-16.