"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
|
| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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A method to probe protein structure from UV absorbance spectra. Anal Biochem. 2019 12 15; 587:113450.
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Esophageal pepsin and proton pump synthesis in barrett's esophagus and esophageal adenocarcinoma. Laryngoscope. 2019 12; 129(12):2687-2695.
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Airway reflux. Ann N Y Acad Sci. 2016 10; 1381(1):5-13.
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Unexpected consequences of proton pump inhibitor use. Otolaryngol Head Neck Surg. 2009 Nov; 141(5):564-6.
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Characterization of von Willebrand factor interaction with collagens in real time using surface plasmon resonance. Ann Biomed Eng. 2002; 30(9):1107-16.
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p200, a collagen secreted by Schwann cells, is expressed in developing nerves and in adult nerves following axotomy. J Neurosci Res. 1999 May 01; 56(3):284-94.
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How accurate is the determination of blood in gastric juice? Comparison of peroxidase and porphyrin methods. Aliment Pharmacol Ther. 1996 Jun; 10(3):333-7.
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Effect of intermittent acid and pepsin exposure on burned esophageal mucosa. Am J Otolaryngol. 1996 Jan-Feb; 17(1):45-9.
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Mechanisms of c-erbB2/neu oncogene-induced metastasis and repression of metastatic properties by adenovirus 5 E1A gene products. Oncogene. 1992 Nov; 7(11):2263-70.
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Effect of red pepper and black pepper on the stomach. Am J Gastroenterol. 1987 Mar; 82(3):211-4.