"Monophenol Monooxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the oxidoreductase class that catalyzes the reaction between L-tyrosine, L-dopa, and oxygen to yield L-dopa, dopaquinone, and water. It is a copper protein that acts also on catechols, catalyzing some of the same reactions as CATECHOL OXIDASE. EC 1.14.18.1.
| Descriptor ID |
D014442
|
| MeSH Number(s) |
D08.811.682.690.708.125.500
|
| Concept/Terms |
Monophenol Monooxygenase- Monophenol Monooxygenase
- Monooxygenase, Monophenol
- Dopa Oxidase
- Oxidase, Dopa
- Phenol Oxidase
- Oxidase, Phenol
- Phenoloxidase
- Tyrosinase
- Cresolase
|
Below are MeSH descriptors whose meaning is more general than "Monophenol Monooxygenase".
Below are MeSH descriptors whose meaning is more specific than "Monophenol Monooxygenase".
This graph shows the total number of publications written about "Monophenol Monooxygenase" by people in this website by year, and whether "Monophenol Monooxygenase" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 3 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Monophenol Monooxygenase" by people in Profiles.
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4H-benzochromene derivatives as novel tyrosinase inhibitors and radical scavengers: synthesis, biological evaluation, and molecular docking analysis. Mol Divers. 2021 Nov; 25(4):2339-2349.
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1,2,3-Triazole-linked 5-benzylidene (thio)barbiturates as novel tyrosinase inhibitors and free-radical scavengers. Arch Pharm (Weinheim). 2020 Oct; 353(10):e2000058.
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Novel morpholine containing cinnamoyl amides as potent tyrosinase inhibitors. Int J Biol Macromol. 2019 Aug 15; 135:978-985.
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Veratric acid derivatives containing benzylidene-hydrazine moieties as promising tyrosinase inhibitors and free radical scavengers. Bioorg Med Chem. 2019 06 15; 27(12):2644-2651.
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Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019 03 07; 10(1):973.
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Synthesis of New Benzimidazole-1,2,3-triazole Hybrids as Tyrosinase Inhibitors. Chem Biodivers. 2018 Jul; 15(7):e1800120.
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Structural insights into the interaction between molluscan hemocyanins and phenolic substrates: An in silico study using docking and molecular dynamics. J Mol Graph Model. 2015 Sep; 61:272-80.
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Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev Biol. 2014 Sep 01; 393(1):3-9.
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PGC-1 coactivators regulate MITF and the tanning response. Mol Cell. 2013 Jan 10; 49(1):145-57.
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Insertional mutagenesis by a hybrid piggyBac and sleeping beauty transposon in the rat. Genetics. 2012 Dec; 192(4):1235-48.