Insulin-Like Growth Factor Binding Protein 1
"Insulin-Like Growth Factor Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
| Descriptor ID |
D018970
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| MeSH Number(s) |
D12.776.157.420.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 1".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in Profiles.
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The SARS-CoV-2 receptor, angiotensin-converting enzyme 2, is required for human endometrial stromal cell decidualization?. Biol Reprod. 2021 02 11; 104(2):336-343.
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Interleukin-13 receptor subunit alpha-2 is a target of progesterone receptor and steroid receptor coactivator-1 in the mouse uterus?. Biol Reprod. 2020 10 05; 103(4):760-768.
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Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
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Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial. Aging Cell. 2016 Feb; 15(1):22-7.
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Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells. Endocrinology. 2015 Jun; 156(6):2239-53.
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The diagnosis of rupture of fetal membranes (ROM): a meta-analysis. J Perinat Med. 2013 May; 41(3):233-40.
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Hypoxia and leucine deprivation induce human insulin-like growth factor binding protein-1 hyperphosphorylation and increase its biological activity. Endocrinology. 2009 Jan; 150(1):220-31.
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High serum IGFBP-2 is predictive of increased bone turnover in aging men and women. J Bone Miner Res. 2007 Jun; 22(6):799-807.
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Low bone mass in subjects on a long-term raw vegetarian diet. Arch Intern Med. 2005 Mar 28; 165(6):684-9.
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A potentially deleterious role of IGFBP-2 on bone density in aging men and women. J Bone Miner Res. 2004 Jul; 19(7):1075-83.