Insulin-Like Growth Factor Binding Protein 5
"Insulin-Like Growth Factor Binding Protein 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
| Descriptor ID |
D018975
|
| MeSH Number(s) |
D12.776.157.420.290
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 5".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 5".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 5" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 3 | 1 | 4 |
| 2009 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 5" by people in Profiles.
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Cognition may link cortical IGFBP5 levels with motor function in older adults. PLoS One. 2019; 14(8):e0220968.
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Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline. Neurobiol Aging. 2019 12; 84:17-25.
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Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons. J Affect Disord. 2019 05 01; 250:313-318.
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Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia. Ann Neurol. 2018 07; 84(1):78-88.
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An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Hum Mol Genet. 2016 09 01; 25(17):3863-3876.
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An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 2014 May 22; 157(5):1104-16.
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The subcellular localization of IGFBP5 affects its cell growth and migration functions in breast cancer. BMC Cancer. 2009 Apr 03; 9:103.
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Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer. Breast Cancer Res. 2008; 10(4):212.
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IGFBP2 and IGFBP5 overexpression correlates with the lymph node metastasis in T1 breast carcinomas. Breast J. 2008 May-Jun; 14(3):261-7.
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Plasma proteome profiling of a mouse model of breast cancer identifies a set of up-regulated proteins in common with human breast cancer cells. J Proteome Res. 2008 Apr; 7(4):1481-9.