Insulin-Like Growth Factor Binding Protein 4
"Insulin-Like Growth Factor Binding Protein 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
| Descriptor ID |
D018974
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| MeSH Number(s) |
D12.776.157.420.280
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 4".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 4".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 4" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 4" by people in Profiles.
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Cross-sectional study of plasma Axl, ferritin, IGFBP4 and sTNFR2 as biomarkers of disease activity in childhood-onset SLE: A study of the Pediatric Nephrology Research Consortium. Lupus. 2021 Aug; 30(9):1394-1404.
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Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis. PLoS One. 2016; 11(3):e0151491.
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SOX9 directly regulates IGFBP-4 in the intestinal epithelium. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 01; 305(1):G74-83.
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Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients. J Transl Med. 2008 Nov 24; 6:70.
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Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells. Oncogene. 2004 Apr 01; 23(14):2454-64.
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Differential gene expression in a murine model of cancer cachexia. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E289-97.
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Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res. 1998 Sep 01; 58(17):4008-14.
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Macrophages synthesize and secrete a 25-kilodalton protein that binds insulin-like growth factor-I. J Immunol. 1996 Jan 01; 156(1):64-72.