"Keratin-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type II keratin found associated with KERATIN-16 or KERATIN-17 in rapidly proliferating squamous epithelial tissue. Mutations in gene for keratin-6A and keratin-6B have been associated with PACHYONYCHIA CONGENITA, TYPE 1 and PACHYONYCHIA CONGENITA, TYPE 2 respectively.
| Descriptor ID |
D053553
|
| MeSH Number(s) |
D05.750.078.593.450.600.600 D12.776.220.475.450.600.600 D12.776.860.607.650.600
|
| Concept/Terms |
Keratin-6- Keratin-6
- Keratin 6
- Cytokeratin-6
- Cytokeratin 6
Keratin-6F- Keratin-6F
- Keratin 6F
- Cytokeratin-6F
- Cytokeratin 6F
Keratin-6E- Keratin-6E
- Keratin 6E
- Cytokeratin-6E
- Cytokeratin 6E
Keratin-6A- Keratin-6A
- Keratin 6A
- Cytokeratin-6A
- Cytokeratin 6A
Keratin-6B- Keratin-6B
- Keratin 6B
- Cytokeratin-6B
- Cytokeratin 6B
|
Below are MeSH descriptors whose meaning is more general than "Keratin-6".
Below are MeSH descriptors whose meaning is more specific than "Keratin-6".
This graph shows the total number of publications written about "Keratin-6" by people in this website by year, and whether "Keratin-6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Keratin-6" by people in Profiles.
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Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype. Int J Biol Sci. 2016; 12(4):381-8.
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Krt6a-positive mammary epithelial progenitors are not at increased vulnerability to tumorigenesis initiated by ErbB2. PLoS One. 2015; 10(1):e0117239.
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Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015 Mar; 46(3):376-83.
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Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409.
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Immunohistochemical characterization of subtypes of male breast carcinoma. Breast Cancer Res. 2009; 11(3):R28.
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The expression of cytokeratin 5/6 in invasive lobular carcinoma of the breast: evidence of a basal-like subset? Hum Pathol. 2008 Mar; 39(3):331-6.
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Immunophenotypic characterization of anal gland carcinoma: loss of p63 and cytokeratin 5/6. Arch Pathol Lab Med. 2007 Aug; 131(8):1304-11.
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Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29.