"Keratin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type II keratin found associated with KERATIN-18 in simple, or predominately single layered, internal epithelia.
| Descriptor ID |
D053533
|
| MeSH Number(s) |
D05.750.078.593.450.600.800 D12.776.220.475.450.600.800 D12.776.860.607.650.800
|
| Concept/Terms |
Keratin-8- Keratin-8
- Keratin 8
- Endo-A Cytokeratin
- Cytokeratin, Endo-A
- Endo A Cytokeratin
- Cytokeratin 8
- Cytokeratin-8
|
Below are MeSH descriptors whose meaning is more general than "Keratin-8".
Below are MeSH descriptors whose meaning is more specific than "Keratin-8".
This graph shows the total number of publications written about "Keratin-8" by people in this website by year, and whether "Keratin-8" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "Keratin-8" by people in Profiles.
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PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol. 2016 Jan 01; 409(1):202-217.
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Tumor necrosis factor-a confers cardioprotection through ectopic expression of keratins K8 and K18. Nat Med. 2015 Sep; 21(9):1076-84.
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FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development. Mol Endocrinol. 2015 Jul; 29(7):1006-24.
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Heterogeneous atypical cell populations are present in blood of metastatic breast cancer patients. Breast Cancer Res. 2014 Mar 06; 16(2):R23.
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Development and characterization of a surgical mouse model of reflux esophagitis and Barrett's esophagus. J Gastrointest Surg. 2014 Feb; 18(2):234-40; discussion 240-1.
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Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis. PLoS One. 2012; 7(6):e38561.
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CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod. 2012 May; 86(5):141, 1-10.
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Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res. 2012 Oct; 21(5):1117-23.
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Loss of keratins 8 and 18 leads to alterations in a6?4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line. J Cell Sci. 2011 Jun 15; 124(Pt 12):2096-106.
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Widespread, exceptionally high levels of histone H3 lysine 4 trimethylation largely mediate "privileged" gene expression. Gene Expr. 2007; 13(4-5):271-82.