Ribonucleoprotein, U4-U6 Small Nuclear
"Ribonucleoprotein, U4-U6 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U4-U6 snRNP along with the U5 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form mature SPLICEOSOMES. There is also evidence for the existence of individual U4 or U6 snRNPs in addition to their organization as a U4-U6 snRNP.
| Descriptor ID |
D017414
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| MeSH Number(s) |
D12.776.157.725.500.875.615 D12.776.664.962.500.875.615
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| Concept/Terms |
Ribonucleoprotein, U4-U6 Small Nuclear- Ribonucleoprotein, U4-U6 Small Nuclear
- Ribonucleoprotein, U4 U6 Small Nuclear
- U4-U6 Small Nuclear Ribonucleoproteins
- U4 U6 Small Nuclear Ribonucleoproteins
- Small Nuclear Ribonucleoproteins, U4-U6
- Small Nuclear Ribonucleoproteins, U4 U6
- U4-U6 snRNP
- Ribonucleoproteins, Small, U4-U6
U6 snRNP- U6 snRNP
- U6 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, U6 Small Nuclear
- Small Nuclear Ribonucleoproteins, U6
U4 snRNP- U4 snRNP
- U4 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, U4 Small Nuclear
- Small Nuclear Ribonucleoproteins, U4
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Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U4-U6 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U4-U6 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U4-U6 Small Nuclear" by people in this website by year, and whether "Ribonucleoprotein, U4-U6 Small Nuclear" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ribonucleoprotein, U4-U6 Small Nuclear" by people in Profiles.
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An Arabidopsis pre-RNA processing8a (prp8a) missense allele restores splicing of a subset of mis-spliced mRNAs. Plant Physiol. 2022 08 01; 189(4):2175-2192.
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A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Rep. 2019 02 05; 26(6):1544-1556.e8.
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The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Genes Dev. 2010 Jul 01; 24(13):1434-47.
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Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst. 1998 Jul 15; 90(14):1080-7.