"Glutathione" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
| Descriptor ID |
D005978
|
| MeSH Number(s) |
D12.644.456.448
|
| Concept/Terms |
Glutathione- Glutathione
- gamma-L-Glutamyl-L-Cysteinylglycine
- gamma L Glutamyl L Cysteinylglycine
- gamma-L-Glu-L-Cys-Gly
- gamma L Glu L Cys Gly
|
Below are MeSH descriptors whose meaning is more general than "Glutathione".
Below are MeSH descriptors whose meaning is more specific than "Glutathione".
This graph shows the total number of publications written about "Glutathione" by people in this website by year, and whether "Glutathione" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 2 | 3 |
| 2000 | 4 | 1 | 5 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 4 | 5 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 3 | 5 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 4 | 6 |
| 2011 | 2 | 4 | 6 |
| 2012 | 6 | 0 | 6 |
| 2013 | 2 | 3 | 5 |
| 2014 | 3 | 3 | 6 |
| 2015 | 3 | 3 | 6 |
| 2016 | 1 | 5 | 6 |
| 2017 | 2 | 2 | 4 |
| 2018 | 5 | 3 | 8 |
| 2019 | 3 | 1 | 4 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 4 | 4 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutathione" by people in Profiles.
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Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart. J Gerontol A Biol Sci Med Sci. 2025 Jan 16; 80(2).
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Pentoxifylline protects memory performance in streptozotocin-induced diabetic rats. Brain Res. 2025 Jan 15; 1847:149319.
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IRE1a determines ferroptosis sensitivity through regulation of glutathione synthesis. Nat Commun. 2024 May 15; 15(1):4114.
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SLC25A39 links mitochondrial GSH sensing with iron metabolism. Mol Cell. 2024 Feb 15; 84(4):616-618.
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Heteroplasmic pathogenic m.12315G>A variant in MT-TL2 presenting with MELAS syndrome and depletion of nitric oxide donors. Am J Med Genet A. 2024 03; 194(3):e63461.
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The deubiquitinase ZRANB1 is an E3 ubiquitin ligase for SLC7A11 and regulates ferroptotic resistance. J Cell Biol. 2023 11 06; 222(11).
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Redox-active polyphenol nanoparticles deprive endogenous glutathione of electrons for ROS generation and tumor chemodynamic therapy. Acta Biomater. 2023 12; 172:423-440.
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ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia. Nat Commun. 2023 09 19; 14(1):5709.
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Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC-MS-Based Metabolomic Approaches. Chem Res Toxicol. 2023 08 21; 36(8):1427-1438.
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Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial. J Gerontol A Biol Sci Med Sci. 2023 01 26; 78(1):75-89.