Hepatocyte Nuclear Factor 6
"Hepatocyte Nuclear Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A onecut transcription factor that regulates expression of GENES involved in EMBRYONIC DEVELOPMENT of the PANCREAS and LIVER.
| Descriptor ID |
D051559
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| MeSH Number(s) |
D12.776.260.262.984 D12.776.260.400.624.500 D12.776.660.352.984 D12.776.930.318.984 D12.776.930.640.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 6".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 6".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 6" by people in this website by year, and whether "Hepatocyte Nuclear Factor 6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 6" by people in Profiles.
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HNF6 and Rev-erba integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms. Genes Dev. 2016 07 15; 30(14):1636-44.
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Kr?ppel-like Factor 4 Blocks Hepatocellular Carcinoma Dedifferentiation and Progression through Activation of Hepatocyte Nuclear Factor-6. Clin Cancer Res. 2016 Jan 15; 22(2):502-12.
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GENE REGULATION. Discrete functions of nuclear receptor Rev-erba couple metabolism to the clock. Science. 2015 Jun 26; 348(6242):1488-92.
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MACE: model based analysis of ChIP-exo. Nucleic Acids Res. 2014 Nov 10; 42(20):e156.
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Loss of HNF6 expression correlates with human pancreatic cancer progression. Lab Invest. 2014 May; 94(5):517-27.
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C/EBPalpha and HNF6 protein complex formation stimulates HNF6-dependent transcription by CBP coactivator recruitment in HepG2 cells. Hepatology. 2006 Feb; 43(2):276-86.
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The cut-homeodomain transcriptional activator HNF-6 is coexpressed with its target gene HNF-3 beta in the developing murine liver and pancreas. Dev Biol. 1997 Dec 15; 192(2):228-46.