"Gene Conversion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another. Thus, e.g., the meiotic products of an Aa individual may be AAAa or aaaA instead of AAaa, i.e., the A allele has been converted into the a allele or vice versa.
Descriptor ID |
D005785
|
MeSH Number(s) |
G05.728.615.475
|
Concept/Terms |
Gene Conversion- Gene Conversion
- Conversion, Gene
- Conversions, Gene
- Gene Conversions
Polar Recombination- Polar Recombination
- Polar Recombinations
- Recombination, Polar
- Recombinations, Polar
|
Below are MeSH descriptors whose meaning is more general than "Gene Conversion".
Below are MeSH descriptors whose meaning is more specific than "Gene Conversion".
This graph shows the total number of publications written about "Gene Conversion" by people in this website by year, and whether "Gene Conversion" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2005 | 1 | 0 | 1 |
2006 | 1 | 2 | 3 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Conversion" by people in Profiles.
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Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA. Proc Natl Acad Sci U S A. 2021 06 22; 118(25).
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Base-Biased Evolution of Disease-Associated Mutations in the Human Genome. Hum Mutat. 2016 11; 37(11):1209-1214.
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Gene conversion of the major histocompatibility complex class I Caja-G in common marmosets (Callithrix jacchus). Immunology. 2016 Nov; 149(3):343-352.
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Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics. Nat Genet. 2014 Oct; 46(10):1072-80.
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Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci. 2012 Sep; 1267:95-102.
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RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol. 2009 May; 11(5):592-603.
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Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell. 2008 Sep 19; 134(6):981-94.
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Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. J Immunol. 2007 Oct 15; 179(8):5274-80.
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Conservative inheritance of newly synthesized DNA in double-strand break-induced gene conversion. Mol Cell Biol. 2006 Dec; 26(24):9424-9.
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A chromosomal rearrangement hotspot can be identified from population genetic variation and is coincident with a hotspot for allelic recombination. Am J Hum Genet. 2006 Nov; 79(5):890-902.