"Gene Conversion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another. Thus, e.g., the meiotic products of an Aa individual may be AAAa or aaaA instead of AAaa, i.e., the A allele has been converted into the a allele or vice versa.
| Descriptor ID |
D005785
|
| MeSH Number(s) |
G05.728.615.475
|
| Concept/Terms |
Gene Conversion- Gene Conversion
- Conversion, Gene
- Conversions, Gene
- Gene Conversions
Polar Recombination- Polar Recombination
- Polar Recombinations
- Recombination, Polar
- Recombinations, Polar
|
Below are MeSH descriptors whose meaning is more general than "Gene Conversion".
Below are MeSH descriptors whose meaning is more specific than "Gene Conversion".
This graph shows the total number of publications written about "Gene Conversion" by people in this website by year, and whether "Gene Conversion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 2 | 3 |
| 2002 | 0 | 2 | 2 |
| 2004 | 2 | 1 | 3 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Conversion" by people in Profiles.
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Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics. Nat Genet. 2014 Oct; 46(10):1072-80.
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Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci. 2012 Sep; 1267:95-102.
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RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol. 2009 May; 11(5):592-603.
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Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. J Immunol. 2007 Oct 15; 179(8):5274-80.
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Genetic exchange between homeologous sequences in mammalian chromosomes is averted by local homology requirements for initiation and resolution of recombination. Genetics. 2006 Sep; 174(1):135-44.
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An apparent interlocus gene conversion-like event at a putative tumor suppressor gene locus on human chromosome 6q27 in a Burkitt's lymphoma cell line. DNA Res. 2000 Aug 31; 7(4):261-72.
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Suppression of experimental autoimmune myasthenia gravis by epitope-specific neonatal tolerance. Adv Exp Med Biol. 1994; 347:65-75.