"Organizers, Embryonic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells in certain regions of an embryo that self-regulate embryonic development. These organizers have been found in dorsal and ventral poles of GASTRULA embryos, including Spemann organizer in amphibians, and Hensen node in chicken and mouse. These organizer cells communicate with each other via a network of secreted signaling proteins, such as BONE MORPHOGENETIC PROTEINS and their antagonists (chordin and noggin).
Descriptor ID |
D020897
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MeSH Number(s) |
A16.675
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Concept/Terms |
Organizers, Embryonic- Organizers, Embryonic
- Embryonic Organizer
- Organizer, Embryonic
- Embryonic Organizers
- Embryo Organizers
- Embryo Organizer
- Organizer, Embryo
- Organizers, Embryo
Hensen Node- Hensen Node
- Node, Hensen
- Hensen's Node
- Hensens Node
- Node, Hensen's
Spemann Organizer- Spemann Organizer
- Organizer, Spemann
- Spemann's Organizer
- Organizer, Spemann's
- Spemanns Organizer
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Below are MeSH descriptors whose meaning is more general than "Organizers, Embryonic".
Below are MeSH descriptors whose meaning is more specific than "Organizers, Embryonic".
This graph shows the total number of publications written about "Organizers, Embryonic" by people in this website by year, and whether "Organizers, Embryonic" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 1 | 2 |
2001 | 1 | 2 | 3 |
2004 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Organizers, Embryonic" by people in Profiles.
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Assay for neural induction in the chick embryo. J Vis Exp. 2009 Feb 13; (24).
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Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 01; 293(1):13-24.
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Diversity of germ layer and axis formation among mammals. Semin Cell Dev Biol. 2004 Oct; 15(5):619-29.
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BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb. Development. 2001 Nov; 128(22):4449-61.
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The organizer of the mouse gastrula is composed of a dynamic population of progenitor cells for the axial mesoderm. Development. 2001 Sep; 128(18):3623-34.
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Electrophysiology of growth control and acupuncture. Life Sci. 2001 Feb 09; 68(12):1333-42.
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Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity. Int J Dev Biol. 2001; 45(1):347-55.
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A beta-catenin/engrailed chimera selectively suppresses Wnt signaling. J Cell Sci. 2000 May; 113 ( Pt 10):1759-70.
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Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature. 2000 Feb 17; 403(6771):781-5.