"Melanocortins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptides derived from pro-opiomelanocortin (POMC) which can stimulate MELANOCYTES or CORTICOTROPHS. Melanocortins include ACTH; ALPHA-MSH; and other peptides such as BETA-MSH and GAMMA-MSH, derived from other fragments of POMC. These peptides act through a variety of MELANOCORTIN RECEPTORS to control different functions including steroidogenesis, energy homeostasis, feeding, and skin pigmentation.
| Descriptor ID |
D053486
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| MeSH Number(s) |
D06.472.699.327.935.531 D06.472.699.631.525.600.531 D12.644.400.400.935.531 D12.644.548.365.935.531 D12.644.548.691.525.690.531 D12.776.631.650.405.935.531
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melanocortins".
Below are MeSH descriptors whose meaning is more specific than "Melanocortins".
This graph shows the total number of publications written about "Melanocortins" by people in this website by year, and whether "Melanocortins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Melanocortins" by people in Profiles.
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Lateral septum as a melanocortin downstream site in obesity development. Cell Rep. 2023 05 30; 42(5):112502.
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The melanocortin action is biased toward protection from weight loss in mice. Nat Commun. 2023 04 17; 14(1):2200.
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The central melanocortin system and human obesity. J Mol Cell Biol. 2020 10 01; 12(10):785-797.
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Circadian Dysfunction Induces Leptin Resistance in Mice. Cell Metab. 2015 Sep 01; 22(3):448-59.
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Central nervous control of energy and glucose balance: focus on the central melanocortin system. Ann N Y Acad Sci. 2011 Dec; 1243:1-14.
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Nicotine decreases food intake through activation of POMC neurons. Science. 2011 Jun 10; 332(6035):1330-2.
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A serotonin and melanocortin circuit mediates D-fenfluramine anorexia. J Neurosci. 2010 Nov 03; 30(44):14630-4.
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An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption. J Lipid Res. 2010 Jul; 51(7):1929-42.
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A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biol Psychiatry. 2010 Jun 01; 67(11):1075-82.
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Starvation after AgRP neuron ablation is independent of melanocortin signaling. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2687-92.