"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
| Descriptor ID |
D047495
|
| MeSH Number(s) |
D12.776.826.239.588
|
| Concept/Terms |
PPAR gamma- PPAR gamma
- PPARgamma
- Thiazolidinedione Receptor
- Receptor, Thiazolidinedione
- Peroxisome Proliferator-Activated Receptor gamma
- Peroxisome Proliferator Activated Receptor gamma
|
Below are MeSH descriptors whose meaning is more general than "PPAR gamma".
Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".
This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 3 | 2 | 5 |
| 2005 | 2 | 3 | 5 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 1 | 3 |
| 2008 | 5 | 1 | 6 |
| 2009 | 3 | 2 | 5 |
| 2010 | 1 | 2 | 3 |
| 2011 | 3 | 5 | 8 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 3 | 4 |
| 2014 | 3 | 1 | 4 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 1 | 3 |
| 2019 | 1 | 4 | 5 |
| 2020 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR gamma" by people in Profiles.
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Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nat Commun. 2024 Aug 02; 15(1):6538.
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[Zhuyu Pills promote polarization of macrophages toward M2 phenotype to prevent atherosclerosis via PPAR?/NF-?B signaling pathway]. Zhongguo Zhong Yao Za Zhi. 2024 Jan; 49(1):243-250.
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Progranulin deficiency suppresses allergic asthma and enhances efferocytosis via PPAR-?/MFG-E8 regulation in macrophages. Immun Inflamm Dis. 2023 02; 11(2):e779.
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Isoform-specific functions of PPAR? in gene regulation and metabolism. Genes Dev. 2022 03 01; 36(5-6):300-312.
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Hypoxia enhances motility and EMT through the Na+/H+ exchanger NHE-1 in MDA-MB-231 breast cancer cells. Exp Cell Res. 2022 03 01; 412(1):113006.
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Cardiolipin-mediated PPAR? S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia. Cell Rep. 2021 02 09; 34(6):108736.
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PPAR?-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension. Circ Res. 2021 02 05; 128(3):401-418.
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Therapeutic Opportunities for Intestinal Angioectasia- Targeting PPAR? and Oxidative Stress. Clin Transl Sci. 2021 03; 14(2):518-528.
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miR-30a targets gene networks that promote browning of human and mouse adipocytes. Am J Physiol Endocrinol Metab. 2020 10 01; 319(4):E667-E677.
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Bisphenol AF promotes inflammation in human white adipocytes. Am J Physiol Cell Physiol. 2020 01 01; 318(1):C63-C72.