"Allylisopropylacetamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein.
| Descriptor ID |
D000502
|
| MeSH Number(s) |
D02.065.064.189 D02.241.081.018.110.189 D02.455.326.271.122.272
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Allylisopropylacetamide".
Below are MeSH descriptors whose meaning is more specific than "Allylisopropylacetamide".
This graph shows the total number of publications written about "Allylisopropylacetamide" by people in this website by year, and whether "Allylisopropylacetamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Allylisopropylacetamide" by people in Profiles.
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Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. Br J Pharmacol. 2003 Feb; 138(4):602-13.
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Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid. Pharm Res. 1999 Oct; 16(10):1582-8.
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Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice. Comp Biochem Physiol B. 1992 May; 102(1):83-5.
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Heme regulation in mouse mammary carcinoma and liver of tumor bearing mice--I. Effect of allyl-isopropylacetamide and veronal on delta-aminolevulinate synthetase, cytochrome P-450 and cytochrome oxidase. Int J Biochem. 1990; 22(9):1005-8.
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In vivo prevention and reversal by the antimitotic colchicine and other related compounds of some porphyrinogenic drug action on heme pathway. Gen Pharmacol. 1990; 21(4):423-6.