Proto-Oncogene Proteins c-raf
"Proto-Oncogene Proteins c-raf" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.
| Descriptor ID |
D019908
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| MeSH Number(s) |
D08.811.913.696.620.682.700.559.842.500 D12.644.360.400.842.500 D12.776.476.400.842.500 D12.776.624.664.700.204.500
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| Concept/Terms |
Proto-Oncogene Proteins c-raf- Proto-Oncogene Proteins c-raf
- Proteins c-raf, Proto-Oncogene
- Proto Oncogene Proteins c raf
- c-raf, Proto-Oncogene Proteins
- Proto-Oncogene Protein c-raf
- Protein c-raf, Proto-Oncogene
- Proto Oncogene Protein c raf
- c-raf, Proto-Oncogene Protein
- c-raf Kinases
- Kinases, c-raf
- c raf Kinases
- Kinase Raf-1
- Kinase Raf 1
- Raf-1, Kinase
- cRaf1 Kinase
- Kinase, cRaf1
- raf-1 Kinase
- Kinase, raf-1
- raf 1 Kinase
- c-raf Proteins
- Proteins, c-raf
- c raf Proteins
- Kinase p74(raf-1)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-raf".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-raf".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-raf" by people in this website by year, and whether "Proto-Oncogene Proteins c-raf" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-raf" by people in Profiles.
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Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation. Exp Cell Res. 2020 09 01; 394(1):111989.
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Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor. Cell Signal. 2020 07; 71:109555.
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Ras acts as a molecular switch between two forms of consolidated memory in Drosophila. Proc Natl Acad Sci U S A. 2020 01 28; 117(4):2133-2139.
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Cardiac transplantation in children with Noonan syndrome. Pediatr Transplant. 2019 09; 23(6):e13535.
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RAF1 variants causing biventricular hypertrophic cardiomyopathy in two preterm infants: further phenotypic delineation and review of literature. Clin Dysmorphol. 2017 Oct; 26(4):195-199.
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PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas. Nature. 2017 10 05; 550(7674):133-136.
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Drug-induced RAF dimerization is independent of RAS mutation status and does not lead to universal MEK dependence for cell survival in head and neck cancers. Anticancer Drugs. 2015 Sep; 26(8):835-42.
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The mammalian Ste20-like kinase 2 (Mst2) modulates stress-induced cardiac hypertrophy. J Biol Chem. 2014 Aug 29; 289(35):24275-88.
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Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib. Clin Cancer Res. 2014 Apr 01; 20(7):1846-55.
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Effects of butyltins on mitogen-activated-protein kinase kinase kinase and Ras activity in human natural killer cells. J Appl Toxicol. 2014 Sep; 34(9):1002-11.