"HLA-DR4 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An HLA-DR antigen which is associated with HLA-DRB1 CHAINS encoded by DRB1*04 alleles.
| Descriptor ID |
D015804
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| MeSH Number(s) |
D12.776.395.550.509.400.440.400.040 D12.776.543.550.440.400.440.400.040 D23.050.301.500.400.400.440.400.040 D23.050.301.500.450.400.440.389.937 D23.050.705.552.410.400.440.389.040 D23.050.705.552.450.400.440.389.937
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "HLA-DR4 Antigen".
Below are MeSH descriptors whose meaning is more specific than "HLA-DR4 Antigen".
This graph shows the total number of publications written about "HLA-DR4 Antigen" by people in this website by year, and whether "HLA-DR4 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-DR4 Antigen" by people in Profiles.
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Characteristics of autoantibody-positive individuals without high-risk HLA-DR4-DQ8 or HLA-DR3-DQ2 haplotypes. Diabetologia. 2025 Mar; 68(3):588-601.
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Aire is not essential for regulating neuroinflammatory disease in mice transgenic for human autoimmune-diseases associated MHC class II genes HLA-DR2b and HLA-DR4. Cell Immunol. 2018 09; 331:38-48.
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Autoreactive T cells in healthy individuals. J Immunol. 2004 May 15; 172(10):5967-72.
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Langerhans cell histiocytosis patients have HLA Cw7 and DR4 types associated with specific clinical presentations and no increased frequency in polymorphisms of the tumor necrosis factor alpha promoter. Med Pediatr Oncol. 2003 Dec; 41(6):502-7.
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HLA-DR4 predicts haematological response to cyclosporine in T-large granular lymphocyte lymphoproliferative disorders. Br J Haematol. 2003 Nov; 123(3):449-53.
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NY-ESO-1 encodes DRB1*0401-restricted epitopes recognized by melanoma-reactive CD4+ T cells. Cancer Res. 2000 Sep 01; 60(17):4946-52.
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Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells. Proc Natl Acad Sci U S A. 2000 Jan 04; 97(1):400-5.
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No linkage or association of telomeric and centromeric T-cell receptor beta-chain markers with susceptibility to type 1 insulin-dependent diabetes in HLA-DR4 multiplex families. Eur J Immunogenet. 1996 Oct; 23(5):361-70.
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Analysis of HLA-D locus alleles in alopecia areata patients and families. J Invest Dermatol. 1995 May; 104(5 Suppl):5S-6S.
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Multigenic basis for type I diabetes. Association of HRAS1 polymorphism with HLA-DR3, DQw2/DR4, DQw8. Diabetes. 1990 Dec; 39(12):1504-9.