"4-Nitroquinoline-1-oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
| Descriptor ID |
D015112
|
| MeSH Number(s) |
D02.640.820.600 D03.633.100.810.470.450 D03.661.243.500
|
| Concept/Terms |
4-Nitroquinoline-1-oxide- 4-Nitroquinoline-1-oxide
- 4 Nitroquinoline 1 oxide
- 4-Nitroquinoline-N-oxide
- 4 Nitroquinoline N oxide
|
Below are MeSH descriptors whose meaning is more general than "4-Nitroquinoline-1-oxide".
Below are MeSH descriptors whose meaning is more specific than "4-Nitroquinoline-1-oxide".
This graph shows the total number of publications written about "4-Nitroquinoline-1-oxide" by people in this website by year, and whether "4-Nitroquinoline-1-oxide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Nitroquinoline-1-oxide" by people in Profiles.
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Local Anti-PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model. Cancer Prev Res (Phila). 2021 08; 14(8):767-778.
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Modeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility. Mol Carcinog. 2014 Aug; 53(8):648-58.
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Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. Mol Carcinog. 2013 Jan; 52(1):49-56.
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Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer. 2011 Jul 15; 129(2):331-45.
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Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents. Hum Genet. 2008 Jul; 123(6):643-53.
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Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. Cancer Res. 2005 Sep 01; 65(17):7790-9.
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Three measures of mutagen sensitivity in a cancer-free population. Cancer Genet Cytogenet. 1999 Apr; 110(1):65-9.
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An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum Genet. 1997 Dec; 101(2):121-5.
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Mutagen sensitivity exhibits a dose-response relationship in case-control studies. Cancer Epidemiol Biomarkers Prev. 1996 Jul; 5(7):577-8.