Matrix Metalloproteinase 14
"Matrix Metalloproteinase 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.
| Descriptor ID |
D053511
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| MeSH Number(s) |
D08.811.277.656.300.480.525.300.500 D08.811.277.656.675.374.525.300.500
|
| Concept/Terms |
Matrix Metalloproteinase 14- Matrix Metalloproteinase 14
- Metalloproteinase 14, Matrix
- Membrane-Type Matrix Metalloproteinase 1
- Membrane Type Matrix Metalloproteinase 1
- MMP-14 Metalloproteinase
- MMP 14 Metalloproteinase
- Metalloproteinase, MMP-14
- MT1-MMP
- MMP14 Metalloproteinase
- Metalloproteinase, MMP14
- MT-MMP-1
- MT1-Matrix Metalloproteinase
- MT1 Matrix Metalloproteinase
- Metalloproteinase, MT1-Matrix
- Membrane-Type 1 Matrix Metalloproteinase
- Membrane Type 1 Matrix Metalloproteinase
- MMP-X1 Protein
- MMP X1 Protein
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Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase 14".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase 14".
This graph shows the total number of publications written about "Matrix Metalloproteinase 14" by people in this website by year, and whether "Matrix Metalloproteinase 14" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Matrix Metalloproteinase 14" by people in Profiles.
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Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death. Int J Mol Sci. 2022 Sep 05; 23(17).
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Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells. Dev Cell. 2017 10 23; 43(2):186-197.e7.
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MT1-MMP-mediated basement membrane remodeling modulates renal development. Exp Cell Res. 2010 Oct 15; 316(17):2993-3005.
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Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through interdependent Cdc42- and MT1-MMP-mediated events. Blood. 2010 Jun 24; 115(25):5259-69.
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MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices. J Cell Sci. 2009 Dec 15; 122(Pt 24):4558-69.
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Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood. 2009 Jul 09; 114(2):237-47.
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Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor. Cancer Metastasis Rev. 2007 Dec; 26(3-4):359-71.
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Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling. Mol Cancer. 2006 Dec 08; 5:69.
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Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2. J Cell Sci. 2002 Feb 15; 115(Pt 4):839-48.