"Porphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
| Descriptor ID |
D011166
|
| MeSH Number(s) |
D03.383.129.578.840.500 D03.633.400.909.500 D04.345.783.500 D23.767.727
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Porphyrins".
Below are MeSH descriptors whose meaning is more specific than "Porphyrins".
This graph shows the total number of publications written about "Porphyrins" by people in this website by year, and whether "Porphyrins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Porphyrins" by people in Profiles.
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Ultra-fast photoelectron transfer in bimetallic porphyrin optoelectrode for single neuron modulation. Nat Commun. 2024 Nov 26; 15(1):10241.
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Bioinspired Design of seco-Chlorin Photosensitizers to Overcome Phototoxic Effects in Photodynamic Therapy. Angew Chem Int Ed Engl. 2022 07 11; 61(28):e202204330.
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Clinical impact of the worldwide shortage of verteporfin (Visudyne?) on ophthalmic care. Acta Ophthalmol. 2022 Nov; 100(7):e1522-e1532.
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Preclinical Evaluation of Cetuximab and Benzoporphyrin Derivative-Mediated Intraperitoneal Photodynamic Therapy in a Canine Model. Photochem Photobiol. 2020 05; 96(3):684-691.
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Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-?B and Its Ligand. ChemMedChem. 2017 10 20; 12(20):1697-1702.
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Rabbit model of ocular indirect photodynamic therapy using a retinoblastoma xenograft. Graefes Arch Clin Exp Ophthalmol. 2017 Dec; 255(12):2363-2373.
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In Vitro Validation of the Hippo Pathway as a Pharmacological Target for Canine Mammary Gland Tumors. J Mammary Gland Biol Neoplasia. 2017 Sep; 22(3):203-214.
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YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway. Cancer Res. 2017 04 01; 77(7):1637-1648.
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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer. Nature. 2016 Oct 06; 538(7623):114-117.
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Intracellular haemolytic agents of Heterocapsa circularisquama exhibit toxic effects on H. circularisquama cells themselves and suppress both cell-mediated haemolytic activity and toxicity to rotifers (Brachionus plicatilis). Aquat Toxicol. 2016 Oct; 179:95-102.