"Acetyl Coenzyme A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
| Descriptor ID |
D000105
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| MeSH Number(s) |
D03.633.100.759.646.138.382.300.020 D08.211.211.300.075 D13.695.667.138.382.300.020 D13.695.827.068.382.300.020
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acetyl Coenzyme A".
Below are MeSH descriptors whose meaning is more specific than "Acetyl Coenzyme A".
This graph shows the total number of publications written about "Acetyl Coenzyme A" by people in this website by year, and whether "Acetyl Coenzyme A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acetyl Coenzyme A" by people in Profiles.
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Advancing de novo lipogenesis: Genetic and metabolic insights. Cell Metab. 2025 Jan 07; 37(1):3-4.
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Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity. mBio. 2024 May 08; 15(5):e0341423.
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ACSS3 regulates the metabolic homeostasis of epithelial cells and alleviates pulmonary fibrosis. Biochim Biophys Acta Mol Basis Dis. 2024 02; 1870(2):166960.
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Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice. J Biol Chem. 2022 10; 298(10):102401.
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Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids. Cell Rep. 2022 05 31; 39(9):110870.
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Acetyl-CoA and Metabolite Fluxes Regulate White Adipose Tissue Expansion. Trends Endocrinol Metab. 2021 05; 32(5):320-332.
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Listeria monocytogenes upregulates mitochondrial calcium signalling to inhibit LC3-associated phagocytosis as a survival strategy. Nat Microbiol. 2021 03; 6(3):366-379.
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AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia. Blood. 2019 12 12; 134(24):2183-2194.
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Organelle-Derived Acetyl-CoA Promotes Prostate Cancer Cell Survival, Migration, and Metastasis via Activation of Calmodulin Kinase II. Cancer Res. 2018 05 15; 78(10):2490-2502.
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KAT2A coupled with the a-KGDH complex acts as a histone H3 succinyltransferase. Nature. 2017 12 14; 552(7684):273-277.