Poly(A)-Binding Protein I
"Poly(A)-Binding Protein I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A poly(A) binding protein that has a variety of functions such as mRNA stabilization and protection of RNA from nuclease activity. Although poly(A) binding protein I is considered a major cytoplasmic RNA-binding protein it is also found in the CELL NUCLEUS and may be involved in transport of mRNP particles.
| Descriptor ID |
D039122
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| MeSH Number(s) |
D12.776.157.725.452.249 D12.776.664.962.452.249
|
| Concept/Terms |
Poly(A)-Binding Protein I- Poly(A)-Binding Protein I
- Poly(A)-Binding Protein, Cytoplasmic 1
- PABP1 Protein
- PABPC1 Protein
- p70 Poly(A) Binding Protein
- PAB1 Poly(A) Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Poly(A)-Binding Protein I".
Below are MeSH descriptors whose meaning is more specific than "Poly(A)-Binding Protein I".
This graph shows the total number of publications written about "Poly(A)-Binding Protein I" by people in this website by year, and whether "Poly(A)-Binding Protein I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Poly(A)-Binding Protein I" by people in Profiles.
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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates. Mol Cell. 2023 Jun 15; 83(12):2020-2034.e6.
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Comprehensive Characterization of Alternative Polyadenylation in Human Cancer. J Natl Cancer Inst. 2018 04 01; 110(4):379-389.
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Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1. J Med Chem. 2012 Nov 26; 55(22):9875-90.
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Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. J Med Chem. 2011 Jul 14; 54(13):4928-32.
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Enzymatic activity is required for the in vivo functions of CARM1. J Biol Chem. 2010 Jan 08; 285(2):1147-52.
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Techniques in protein methylation. Methods Mol Biol. 2004; 284:195-208.
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Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6464-8.