"Inteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
| Descriptor ID |
D047668
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| MeSH Number(s) |
G02.111.570.060.440
|
| Concept/Terms |
Inteins- Inteins
- Intein
- Protein Introns
- Intervening Protein Sequence
- Intervening Protein Sequences
- Protein Sequence, Intervening
- Protein Sequences, Intervening
- Sequence, Intervening Protein
- Sequences, Intervening Protein
- Introns, Protein
- Intron, Protein
- Protein Intron
|
Below are MeSH descriptors whose meaning is more general than "Inteins".
Below are MeSH descriptors whose meaning is more specific than "Inteins".
This graph shows the total number of publications written about "Inteins" by people in this website by year, and whether "Inteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inteins" by people in Profiles.
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Short intronic repeat sequences facilitate circular RNA production. Genes Dev. 2014 Oct 15; 28(20):2233-47.
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Expressed protein ligation for the preparation of fusion proteins with cell penetrating peptides for endotoxin removal and intracellular delivery. Biochim Biophys Acta. 2010 Dec; 1798(12):2249-57.
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Sequencing the full-length of the phosphatase and tensin homolog (PTEN) gene in hepatocellular carcinoma (HCC) using the 454 GS20 and Illumina GA DNA sequencing platforms. World J Surg. 2009 Apr; 33(4):647-52.