Myelin Proteolipid Protein
"Myelin Proteolipid Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A myelin protein that is the major component of the organic solvent extractable lipoprotein complexes of whole brain. It has been the subject of much study because of its unusual physical properties. It remains soluble in chloroform even after essentially all of its bound lipids have been removed. (From Siegel et al., Basic Neurochemistry, 4th ed, p122)
| Descriptor ID |
D018991
|
| MeSH Number(s) |
D10.570.780.500 D12.776.543.620.580 D12.776.631.580.580 D12.776.816.500
|
| Concept/Terms |
Myelin Proteolipid Protein- Myelin Proteolipid Protein
- Folch-Lees Protein
- Folch Lees Protein
- Protein, Folch-Lees
- Proteolipid Protein, Myelin
- Protein, Myelin Proteolipid
- Folch-PI Proteolipid Protein
- Folch PI Proteolipid Protein
- Protein, Folch-PI Proteolipid
- Proteolipid Protein, Folch-PI
- Myelin PLP
- PLP, Myelin
|
Below are MeSH descriptors whose meaning is more general than "Myelin Proteolipid Protein".
Below are MeSH descriptors whose meaning is more specific than "Myelin Proteolipid Protein".
This graph shows the total number of publications written about "Myelin Proteolipid Protein" by people in this website by year, and whether "Myelin Proteolipid Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 3 | 0 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myelin Proteolipid Protein" by people in Profiles.
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Distinct patterns of complex rearrangements and a mutational signature of microhomeology are frequently observed in PLP1 copy number gain structural variants. Genome Med. 2019 12 09; 11(1):80.
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Complex genomic rearrangements at the PLP1 locus include triplication and quadruplication. PLoS Genet. 2015 Mar; 11(3):e1005050.
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Disruption of estrous cycle homeostasis in mice with experimental autoimmune encephalomyelitis. J Neuroimmunol. 2015 Feb 15; 279:71-4.
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Pelizaeus-Merzbacher disease-associated proteolipid protein 1 inhibits oligodendrocyte precursor cell differentiation via extracellular-signal regulated kinase signaling. Biochem Biophys Res Commun. 2012 Jul 27; 424(2):262-8.
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High frequency of GJA12/GJC2 mutations in Turkish patients with Pelizaeus-Merzbacher disease. Clin Genet. 2013 Jan; 83(1):66-72.
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Evidence for disease penetrance relating to CNV size: Pelizaeus-Merzbacher disease and manifesting carriers with a familial 11 Mb duplication at Xq22. Clin Genet. 2012 Jun; 81(6):532-41.
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In trans T cell tolerance diminishes autoantibody responses and exacerbates experimental allergic encephalomyelitis. J Immunol. 2008 Feb 01; 180(3):1508-16.
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A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell. 2007 Dec 28; 131(7):1235-47.
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Role of genomic architecture in PLP1 duplication causing Pelizaeus-Merzbacher disease. Hum Mol Genet. 2006 Jul 15; 15(14):2250-65.
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Prenatal diagnosis of PLP1 copy number by array comparative genomic hybridization. Prenat Diagn. 2005 Dec; 25(13):1188-91.