Sterol Regulatory Element Binding Protein 2
"Sterol Regulatory Element Binding Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sterol regulatory element binding protein that regulates GENES involved in CHOLESTEROL synthesis and uptake.
| Descriptor ID |
D051782
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| MeSH Number(s) |
D12.776.260.103.500.750.750 D12.776.260.108.092.750.750 D12.776.930.125.500.750.750 D12.776.930.127.092.750.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sterol Regulatory Element Binding Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Sterol Regulatory Element Binding Protein 2".
This graph shows the total number of publications written about "Sterol Regulatory Element Binding Protein 2" by people in this website by year, and whether "Sterol Regulatory Element Binding Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sterol Regulatory Element Binding Protein 2" by people in Profiles.
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Dominant missense variants in SREBF2 are associated with complex dermatological, neurological, and skeletal abnormalities. Genet Med. 2024 Sep; 26(9):101174.
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Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake. Neuro Oncol. 2023 09 05; 25(9):1578-1591.
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Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. Nat Commun. 2021 05 21; 12(1):3005.
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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis. Elife. 2021 05 04; 10.
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The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis. Nature. 2020 04; 580(7804):530-535.
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Absence of gravin-mediated signaling inhibits development of high-fat diet-induced hyperlipidemia and atherosclerosis. Am J Physiol Heart Circ Physiol. 2019 10 01; 317(4):H793-H810.
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The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORa/?. Genes Dev. 2017 06 15; 31(12):1202-1211.
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CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer. Cancer Res. 2017 04 01; 77(7):1662-1673.
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Flow signaling and atherosclerosis. Cell Mol Life Sci. 2017 05; 74(10):1835-1858.
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Inflammatory stress reduces the effectiveness of statins in the kidney by disrupting HMGCoA reductase feedback regulation. Nephrol Dial Transplant. 2014 Oct; 29(10):1864-78.