"Benzo(a)pyrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
| Descriptor ID |
D001564
|
| MeSH Number(s) |
D02.455.426.559.847.799.306.300 D04.615.799.306.300
|
| Concept/Terms |
Benzo(a)pyrene- Benzo(a)pyrene
- 3,4-Benzpyrene
- 3,4 Benzpyrene
- 3,4-Benzopyrene
- 3,4 Benzopyrene
|
Below are MeSH descriptors whose meaning is more general than "Benzo(a)pyrene".
Below are MeSH descriptors whose meaning is more specific than "Benzo(a)pyrene".
This graph shows the total number of publications written about "Benzo(a)pyrene" by people in this website by year, and whether "Benzo(a)pyrene" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Benzo(a)pyrene" by people in Profiles.
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PKCe Is Required for KRAS-Driven Lung Tumorigenesis. Cancer Res. 2020 12 01; 80(23):5166-5173.
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Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer Prev Res (Phila). 2017 Oct; 10(10):588-597.
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Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures. Arch Toxicol. 2015 Jun; 89(6):967-77.
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Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. Mol Carcinog. 2015 Oct; 54(10):1060-9.
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Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014 Oct 15; 230(2):322-32.
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Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma. Am J Clin Nutr. 2012 Jan; 95(1):155-62.
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Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: implications for cancer prevention. Toxicol Appl Pharmacol. 2010 Dec 15; 249(3):224-30.
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Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice. Cancer Prev Res (Phila). 2008 Nov; 1(6):430-8.
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An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. J Neurochem. 2007 Aug; 102(3):867-77.
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Dietary mutagen exposure and risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev. 2007 Apr; 16(4):655-61.