"Benzo(a)pyrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
| Descriptor ID |
D001564
|
| MeSH Number(s) |
D02.455.426.559.847.799.306.300 D04.615.799.306.300
|
| Concept/Terms |
Benzo(a)pyrene- Benzo(a)pyrene
- 3,4-Benzpyrene
- 3,4 Benzpyrene
- 3,4-Benzopyrene
- 3,4 Benzopyrene
|
Below are MeSH descriptors whose meaning is more general than "Benzo(a)pyrene".
Below are MeSH descriptors whose meaning is more specific than "Benzo(a)pyrene".
This graph shows the total number of publications written about "Benzo(a)pyrene" by people in this website by year, and whether "Benzo(a)pyrene" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Benzo(a)pyrene" by people in Profiles.
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Placental Polycyclic Aromatic Hydrocarbon (PAH) Levels Are Associated with Spontaneous Preterm Birth. Int J Mol Sci. 2025 Aug 23; 26(17).
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Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer Prev Res (Phila). 2017 Oct; 10(10):588-597.
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Mechanistic relationships between hepatic genotoxicity and carcinogenicity in male B6C3F1 mice treated with polycyclic aromatic hydrocarbon mixtures. Arch Toxicol. 2015 Jun; 89(6):967-77.
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Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014 Oct 15; 230(2):322-32.
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Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma. Am J Clin Nutr. 2012 Jan; 95(1):155-62.
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Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: implications for cancer prevention. Toxicol Appl Pharmacol. 2010 Dec 15; 249(3):224-30.
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An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. J Neurochem. 2007 Aug; 102(3):867-77.
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Dietary mutagen exposure and risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev. 2007 Apr; 16(4):655-61.
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Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J Natl Cancer Inst. 2005 Nov 16; 97(22):1695-9.
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Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis. Cancer Res. 2005 Mar 15; 65(6):2054-8.