"Spermine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
| Descriptor ID |
D013096
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| MeSH Number(s) |
D02.092.211.415.701.801.821 D02.092.782.802
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermine".
Below are MeSH descriptors whose meaning is more specific than "Spermine".
This graph shows the total number of publications written about "Spermine" by people in this website by year, and whether "Spermine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spermine" by people in Profiles.
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Effectiveness of COVID-19 vaccines at preventing emergency department or urgent care encounters and hospitalizations among immunocompromised adults: An observational study of real-world data across 10 US states from August-December 2021. Vaccine. 2023 08 23; 41(37):5424-5434.
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Spermine promotes pulmonary vascular remodelling and its synthase is a therapeutic target for pulmonary arterial hypertension. Eur Respir J. 2020 11; 56(5).
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Association Between Plasma Diacetylspermine and Tumor Spermine Synthase With Outcome in Triple-Negative Breast Cancer. J Natl Cancer Inst. 2020 06 01; 112(6):607-616.
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Spermine Sepharose as a clustered-charge anion exchange adsorbent. J Chromatogr A. 2014 Jan 10; 1324:135-40.
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Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):E2950-7.
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Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma. Int J Oncol. 2007 Aug; 31(2):431-40.
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Nitric oxide (NO) upregulates NO synthase expression in fetal intrapulmonary artery endothelial cells. Am J Respir Cell Mol Biol. 1999 Nov; 21(5):629-36.
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Comparison of chromosomal structures isolated under different conditions. Exp Cell Res. 1982 Mar; 138(1):221-9.