"Phleomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Water-soluble, copper-containing low molecular weight polypeptides obtained from the culture medium of Streptomyces verticillus. They are specific inhibitors of DNA synthesis in bacteria and have been found to act as antitumor agents. They have also been used against rust fungi of plants.
| Descriptor ID |
D010692
|
| MeSH Number(s) |
D09.400.420.110.710 D12.644.233.110.710
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phleomycins".
Below are MeSH descriptors whose meaning is more specific than "Phleomycins".
This graph shows the total number of publications written about "Phleomycins" by people in this website by year, and whether "Phleomycins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phleomycins" by people in Profiles.
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Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble. Nat Commun. 2022 01 18; 13(1):359.
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Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells. DNA Repair (Amst). 2018 12; 72:86-92.
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Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. Mol Cell Biol. 2004 Nov; 24(22):10016-25.
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The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment. Nucleic Acids Res. 2003 Mar 15; 31(6):1715-24.