Methylnitronitrosoguanidine
"Methylnitronitrosoguanidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties.
| Descriptor ID |
D008769
|
| MeSH Number(s) |
D02.078.370.649.400 D02.654.567.400
|
| Concept/Terms |
Methylnitronitrosoguanidine- Methylnitronitrosoguanidine
- Nitrosonitromethylguanidine
- N-Methyl-N'-nitro-N-nitrosoguanidine
- N Methyl N' nitro N nitrosoguanidine
- Nitrosomethylnitroguanidine
- Methylnitrosonitroguanidine
- MNNG
|
Below are MeSH descriptors whose meaning is more general than "Methylnitronitrosoguanidine".
Below are MeSH descriptors whose meaning is more specific than "Methylnitronitrosoguanidine".
This graph shows the total number of publications written about "Methylnitronitrosoguanidine" by people in this website by year, and whether "Methylnitronitrosoguanidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylnitronitrosoguanidine" by people in Profiles.
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PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons. Neurochem Int. 2021 09; 148:105077.
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Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines. Mol Cell. 2012 Jul 13; 47(1):50-60.
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Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses. J Biol Chem. 2008 Aug 01; 283(31):21382-93.
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N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA. Mol Cancer. 2004 Jan 16; 3:3.
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MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15387-92.
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DNA damage-induced cell cycle checkpoints involve both p53-dependent and -independent pathways: role of telomere repeat binding factor 2. Br J Cancer. 2001 Sep 14; 85(6):898-901.
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Garlic and neem leaf extracts enhance hepatic glutathione and glutathione dependent enzymes during N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis in rats. Phytother Res. 2000 Jun; 14(4):291-3.
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Modulatory effects of garlic and neem leaf extracts on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced oxidative stress in Wistar rats. Cell Biochem Funct. 2000 Mar; 18(1):17-21.
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In situ staining for poly(ADP-ribose) polymerase activity using an NAD analogue. J Histochem Cytochem. 1998 Nov; 46(11):1279-89.
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Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization. Differentiation. 1997 Aug; 61(5):321-31.