"Isradipine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Descriptor ID |
D017275
|
| MeSH Number(s) |
D03.383.725.203.310
|
| Concept/Terms |
PN-205-033- PN-205-033
- PN 205 033
- PN205033
- PN 205-033
- PN 205033
PN 205-034- PN 205-034
- PN 205 034
- PN 205034
- PN-205-034
- PN205034
|
Below are MeSH descriptors whose meaning is more general than "Isradipine".
Below are MeSH descriptors whose meaning is more specific than "Isradipine".
This graph shows the total number of publications written about "Isradipine" by people in this website by year, and whether "Isradipine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Isradipine" by people in Profiles.
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Isradipine and dextromethorphan in methadone-maintained humans under a naloxone discrimination procedure. Eur J Pharmacol. 2004 May 03; 491(2-3):157-68.
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Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacol Biochem Behav. 2003 Jul; 75(4):801-8.
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Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. Am J Addict. 2002; 11(3):200-8.
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L-type calcium channels mediate dynorphin neuropeptide release from dendrites but not axons of hippocampal granule cells. Neuron. 1995 Jun; 14(6):1265-72.
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Inhibition of dihydropyridine-sensitive calcium channels by the plant alkaloid ryanodine. FEBS Lett. 1989 Feb 27; 244(2):333-7.
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Antihypertensive activity of isradipine in humans: a new dihydropyridine calcium channel antagonist. Clin Pharmacol Ther. 1986 Dec; 40(6):694-7.
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Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110. Circ Res. 1986 Feb; 58(2):305-9.