Pregnenolone Carbonitrile
"Pregnenolone Carbonitrile" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the potential for protective capability against acetaminophen-induced liver damage.
Descriptor ID |
D011285
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MeSH Number(s) |
D02.626.745 D04.210.500.745.745.725.703
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Concept/Terms |
Pregnenolone Carbonitrile- Pregnenolone Carbonitrile
- Carbonitrile, Pregnenolone
- Pregnenolone 16 alpha-Carbonitrile
- 16 alpha-Carbonitrile, Pregnenolone
- Pregnenolone 16 alpha Carbonitrile
- PCN
|
Below are MeSH descriptors whose meaning is more general than "Pregnenolone Carbonitrile".
Below are MeSH descriptors whose meaning is more specific than "Pregnenolone Carbonitrile".
This graph shows the total number of publications written about "Pregnenolone Carbonitrile" by people in this website by year, and whether "Pregnenolone Carbonitrile" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pregnenolone Carbonitrile" by people in Profiles.
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Effects of cytochrome P450 inducers on tamoxifen genotoxicity in female mice in vivo. Biochem Pharmacol. 1997 Mar 07; 53(5):663-9.
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Effects of cytochrome P450 inducers on I-compounds in rat liver and kidney DNA. Carcinogenesis. 1992 Jul; 13(7):1191-8.
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Sex-specific modulation of hepatic covalent DNA modifications (I-compounds) by the cytochrome P450 inducer, pregnenolone-16 alpha-carbonitrile. Toxicol Appl Pharmacol. 1992 Apr; 113(2):218-26.