"RNA Polymerase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin.
| Descriptor ID |
D012318
|
| MeSH Number(s) |
D08.811.913.696.445.735.270.750
|
| Concept/Terms |
RNA Polymerase I- RNA Polymerase I
- Polymerase I, RNA
- DNA-Dependent RNA Polymerase I
- DNA Dependent RNA Polymerase I
- RNA Polymerase A
- Polymerase A, RNA
|
Below are MeSH descriptors whose meaning is more general than "RNA Polymerase I".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase I".
This graph shows the total number of publications written about "RNA Polymerase I" by people in this website by year, and whether "RNA Polymerase I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA Polymerase I" by people in Profiles.
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Control of ribosomal RNA synthesis by hematopoietic transcription factors. Mol Cell. 2022 10 20; 82(20):3826-3839.e9.
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Physiological roles for mafr-1 in reproduction and lipid homeostasis. Cell Rep. 2014 Dec 24; 9(6):2180-91.
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Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes. Cancer Res. 2011 Jun 15; 71(12):4269-79.
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Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. Mol Cell. 2007 May 11; 26(3):367-79.
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PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. Mol Cell Biol. 2005 Aug; 25(16):6899-911.
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Epidermal growth factor enhances cellular TATA binding protein levels and induces RNA polymerase I- and III-dependent gene activity. Mol Cell Biol. 2004 Jun; 24(12):5119-29.
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Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding protein. Mol Cell Biol. 1998 Dec; 18(12):7086-94.
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Global alterations in chromatin accessibility associated with loss of SIN4 function. Nucleic Acids Res. 1997 Mar 15; 25(6):1240-7.
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Identification of previously unrecognized common elements in eukaryotic promoters. A ribosomal RNA gene initiator element for RNA polymerase I. J Biol Chem. 1997 Feb 07; 272(6):3141-4.
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Isolation and characterization of nonhistone chromosomal protein C-14 which stimulates RNA synthesis. Biochemistry. 1977 May 31; 16(11):2384-9.