Ribosomal Protein S6 Kinases, 90-kDa
"Ribosomal Protein S6 Kinases, 90-kDa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN.
| Descriptor ID |
D038744
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.862.500 D12.644.360.600.500 D12.776.476.600.500
|
| Concept/Terms |
Ribosomal Protein S6 Kinases, 90-kDa- Ribosomal Protein S6 Kinases, 90-kDa
- Ribosomal Protein S6 Kinases, 90 kDa
- p90(rsk)
- MAP-Kinase-Activated Protein Kinase 1
- MAP Kinase Activated Protein Kinase 1
- MAPKAP Kinase-1
- MAPKAP Kinase 1
- MAP-Kinase-Activated Kinase 1
- MAP Kinase Activated Kinase 1
- Ribosomal Protein S6 Kinase, 90-kDa
- Ribosomal Protein S6 Kinase, 90 kDa
- p90 Ribosomal S6 Kinase
- MAPKAP-K1
- pp90(rsk)
- MAPKAPK1
|
Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6 Kinases, 90-kDa".
Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6 Kinases, 90-kDa".
This graph shows the total number of publications written about "Ribosomal Protein S6 Kinases, 90-kDa" by people in this website by year, and whether "Ribosomal Protein S6 Kinases, 90-kDa" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Ribosomal Protein S6 Kinases, 90-kDa" by people in Profiles.
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Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1. EMBO J. 2021 04 01; 40(7):e106106.
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Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase. Nat Commun. 2021 02 09; 12(1):896.
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Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs. Am J Physiol Endocrinol Metab. 2016 04 15; 310(8):E699-E713.
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Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes. Acta Neuropathol Commun. 2014 Dec 20; 2:160.
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Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer. Oncogene. 2014 May 29; 33(22):2846-56.
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RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1. Nature. 2013 Jun 20; 498(7454):325-331.
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RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 2014 May 01; 33(18):2385-94.
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Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention. Clin Cancer Res. 2012 Jul 01; 18(13):3705-13.
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Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19885-90.
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Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. J Neurochem. 2007 Aug; 102(3):957-66.