"5' Untranslated Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.
| Descriptor ID |
D020121
|
| MeSH Number(s) |
D13.444.735.544.875.885 D13.444.735.790.878.885 G05.360.340.024.220.880.885 G05.360.340.024.340.137.910.885
|
| Concept/Terms |
5' Untranslated Regions- 5' Untranslated Regions
- 5' Untranslated Region
- Region, 5' Untranslated
- Regions, 5' Untranslated
- Untranslated Region, 5'
- Untranslated Regions, 5'
- 5'UTR
- 5'UTRs
- Leader Sequences, mRNA
- Leader Sequence, mRNA
- Sequence, mRNA Leader
- Sequences, mRNA Leader
- mRNA Leader Sequence
- mRNA Leader Sequences
- 5' UTR
- 5' UTRs
- UTR, 5'
- UTRs, 5'
- Leader mRNA Sequences
- Leader mRNA Sequence
- Sequence, Leader mRNA
- Sequences, Leader mRNA
- mRNA Sequence, Leader
- mRNA Sequences, Leader
|
Below are MeSH descriptors whose meaning is more general than "5' Untranslated Regions".
Below are MeSH descriptors whose meaning is more specific than "5' Untranslated Regions".
This graph shows the total number of publications written about "5' Untranslated Regions" by people in this website by year, and whether "5' Untranslated Regions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 5 | 6 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 3 | 4 |
| 2003 | 3 | 3 | 6 |
| 2004 | 2 | 7 | 9 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 2 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 6 | 6 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 2 | 3 |
| 2022 | 0 | 2 | 2 |
| 2024 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "5' Untranslated Regions" by people in Profiles.
-
Deletions in the CDKL5 5' untranslated region lead to CDKL5 deficiency disorder. Am J Med Genet A. 2025 Jan; 197(1):e63843.
-
Control of mammalian gene expression by modulation of polyA signal cleavage at 5' UTR. Nat Biotechnol. 2024 Sep; 42(9):1454-1466.
-
Global 5'-UTR RNA structure regulates translation of a SERPINA1 mRNA. Nucleic Acids Res. 2022 09 23; 50(17):9689-9704.
-
Small molecule-based detection of non-canonical RNA G-quadruplex structures that modulate protein translation. Nucleic Acids Res. 2022 08 12; 50(14):8143-8153.
-
Concordant Androgen-Regulated Expression of Divergent Rhox5 Promoters in Sertoli Cells. Endocrinology. 2022 01 01; 163(1).
-
Selective packaging of HIV-1 RNA genome is guided by the stability of 5' untranslated region polyA stem. Proc Natl Acad Sci U S A. 2021 12 14; 118(50).
-
YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell. 2020 12 14; 38(6):857-871.e7.
-
Unpaired Guanosines in the 5' Untranslated Region of HIV-1 RNA Act Synergistically To Mediate Genome Packaging. J Virol. 2020 10 14; 94(21).
-
miR760 regulates ATXN1 levels via interaction with its 5' untranslated region. Genes Dev. 2020 09 01; 34(17-18):1147-1160.
-
Study of telomere length in men who carry a fragile X premutation or full mutation allele. Hum Genet. 2020 Dec; 139(12):1531-1539.