"Chlorambucil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
| Descriptor ID |
D002699
|
| MeSH Number(s) |
D02.455.526.728.650.156
|
| Concept/Terms |
Chlorambucil- Chlorambucil
- 4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid
- N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid
- Chloraminophene
- Chlorbutin
|
Below are MeSH descriptors whose meaning is more general than "Chlorambucil".
Below are MeSH descriptors whose meaning is more specific than "Chlorambucil".
This graph shows the total number of publications written about "Chlorambucil" by people in this website by year, and whether "Chlorambucil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chlorambucil" by people in Profiles.
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Oxidized Activated Charcoal Nanozymes: Synthesis, and Optimization for In Vitro and In Vivo Bioactivity for Traumatic Brain Injury. Adv Mater. 2024 Mar; 36(10):e2211239.
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Does older age justify chlorambucil control arms for chronic lymphocytic leukemia clinical trials: a SEER-Medicare analysis. Leukemia. 2023 07; 37(7):1558-1560.
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Drug resistance to chlorambucil in murine B-cell leukemic cells is overcome by its conjugation to a targeting peptide. Anticancer Drugs. 2013 Feb; 24(2):112-9.
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Rituximab in lymphocyte predominance Hodgkin's disease: a case series. Clin Lymphoma. 2003 Sep; 4(2):115-8.
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Why do drugs work in CLL? Leuk Lymphoma. 1996 Oct; 22 Suppl 2:1-11.
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Acquired immune deficiency, myelodysplasia, and acute nonlymphocytic leukemia associated with monosomy 7 and t(3;3) (q21;q26) in a child with Langerhans cell histiocytosis. Am J Pediatr Hematol Oncol. 1989; 11(2):153-7.