"Mechlorethamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
| Descriptor ID |
D008466
|
| MeSH Number(s) |
D02.455.526.728.650.529
|
| Concept/Terms |
Mechlorethamine- Mechlorethamine
- Chlormethine
- Bis(2-chloroethyl)methylamine
- Mustine
- Nitrogen Mustard
- Chlorethazine
- Methylchlorethamine
Mechlorethamine Hydrochloride N-Oxide- Mechlorethamine Hydrochloride N-Oxide
- Hydrochloride N-Oxide, Mechlorethamine
- Mechlorethamine Hydrochloride N Oxide
- N-Oxide, Mechlorethamine Hydrochloride
Mechlorethamine N-Oxide- Mechlorethamine N-Oxide
- Mechlorethamine N Oxide
- Nitrogen Mustard N-Oxide
- N-Oxide, Nitrogen Mustard
- Nitrogen Mustard N Oxide
|
Below are MeSH descriptors whose meaning is more general than "Mechlorethamine".
Below are MeSH descriptors whose meaning is more specific than "Mechlorethamine".
This graph shows the total number of publications written about "Mechlorethamine" by people in this website by year, and whether "Mechlorethamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mechlorethamine" by people in Profiles.
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Erythema gyratum repens-like eruptions with large cell transformation in a patient with mycosis fungoides. Int J Dermatol. 2012 Oct; 51(10):1231-3.
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Vanishing bile duct syndrome and Hodgkin disease: a case series and review of the literature. J Pediatr Hematol Oncol. 2008 Dec; 30(12):976-80.
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Current treatment of Cutaneous T-Cell Lymphoma. Dermatol Online J. 2001 Feb; 7(1):3.
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Combined modality therapy for cutaneous T-cell lymphoma. J Am Acad Dermatol. 1996 Jun; 34(6):1022-9.
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Treatment of early stages of Hodgkin's disease with novantrone, vincristine, vinblastine, prednisone, and radiotherapy. Semin Hematol. 1994 Apr; 31(2 Suppl 3):36-43.
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Hodgkin's disease with a mediastinal mass greater than 10 cm: results of four different treatment approaches. Ann Oncol. 1994; 5 Suppl 2:97-100.
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Hodgkin's disease associated with central pontine myelinolysis. Med Pediatr Oncol. 1993; 21(4):311-4.
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Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. J Neurooncol. 1992 Sep; 14(1):57-62.
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Two cycles of MOPP and radiotherapy: effective treatment for stage IIIA and IIIB Hodgkin's disease. Ann Oncol. 1991 Jan; 2(1):25-31.
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Hodgkin's disease presenting in the skin: case report and review of the literature. J Am Acad Dermatol. 1990 May; 22(5 Pt 2):944-7.